Several ID/HIV items to contemplate as the heat really kicks in here in the torrid USA:
TDF/FTC approved for pre-exposure prophylaxis. The challenging issues of defining the best candidates for this strategy — and finding the providers to prescribe it — still remain, but FDA approval should at least help justify insurance coverage if clinicians choose to offer it to their patients. Some other controversies? Sure!
Dolutegravir + abacavir/lamivudine bests TDF/FTC/EFV. All the info we have thus far is in the press release , but let the record show that this will be the first time a regimen is significantly better than TDF/FTC/EFV in its primary analysis. The results are driven by more discontinuations for adverse events in the EFV arm. Further details eagerly awaited.
Severe Hand, Foot, and Mouth Disease outbreak in Asia. It’s apparently caused by enterovirus-71 , and to me it’s still perplexing — despite what this brief article in our local paper says.
Toxoplasmosis linked to suicide risk. I’m a big believer that many chronic infections are in fact benign — we live with microbes, remember? — but data linking CMV and now toxoplasmosis with adverse outcomes are now out there (here, toxo associated with “self-directed violence” — haven’t heard that one before). And all ID docs know that it’s more appropriate to blame your diet than your cat, right? Last, I’ll say it again — is there a better name for a scary Infectious Disease than Toxoplasmosis gondii? Yikes, just saying it makes me frightened.
Bad tick-related illness season. That was a completely anecdotal impression, my apologies for no reference.