A. Remodulin (treprostinil) is another IV or subcutaneous (under the skin) delivered medication in the treatment of pulmonary hypertension. Remodulin was FDA-approved in 2002. Remodulin is a vasodilator, and helps widen the blood vessels of the lungs and other parts of the body. Remodulin has been shown to improve exercise capacity only a few months after a PHer is on it.
Remodulin's half-life is much longer than Flolan's. Instead of disappearing minutes after being delivered into the body (like Flolan), it can last up to 4 hours. As with Flolan, precautions need to be taken to keep the environment sterile when preparing for dressing changes. The biggest issue many Remodulin users deal with is site pain, which usually lessens the longer it is used.