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Passion For Eradication: Part Deux

Posted Aug 24 2008 7:26pm
Why does TYP (Track Your Plaque) work? (Part 2)



Seminal articles published much earlier than Dr. Davis’ Track Your Plaque tome provided a framework for which success could be elaborated upon... yet none of these progressively written testaments yielded solid, concrete solutions such as Dr.Davis’s TYP program.



The program he devised is actually dynamic.... changing with progress, newly eludicated outcomes and observations from the literature and experience. Constantly evolving and improving the program, Dr. 'D' shares his thoughts liberally on his HeartScanBlog as well as on comprehensive updates on the TrackYourPlaque website.



Heart disease is being reversed on a daily basis with his powerful TrackYourPlaque plan. Members and participants (and myself) often wonder on the TYP forum and HeartScanBlog when will Dr. Davis be awarded the Nobel...



The coronary risk factors have all been discovered and discussed in major medical journals by well-known experts in the field for a decade now, but a complete package of viable solutions (and manners of identification of heart disease) have seemed to fail to come to fruition in national consensus guidelines that would effectively improve care in primary and secondary cardiovascular disease prevention.



Why?



Beyond bandaid-statins and common coronary surgeries, which do little to correct underlying disease processes, what exists that actually works? Why is coronary artery disease still the #1 killer in America... and strokes #3? Why aren't these stats changing (and seem to get worse, especially for women)? Why is CAD not being broadly reversed with the huge resources and high-tech approaches currently available in our great country??



Because Dr. Davis emphasizes the use of a convenient, low-radiation diagnostic tool --- the EBT heart scans --- to guide and dictate therapy, the only plan and protocol for effective plaque reversal that has a true TRACK record of success is of course T-Y-P.



Is seeing is not believing when plaque is present? Usually unfortunately... affirmative... (unless you're symptomatic with anginal pain or erectile dysfunction (future blog topic)). TYP optimizes each and every risk factor identified at this time (in addition to 'new' risk factors that Dr.Davis may find emerging later). Predicting potential penetrating plaque-producers (now... say that 10x) is the key to knowing what elements you are dealing with.



These are subsequently quenched... For a lifetime…



Proatherogenic mechanisms and progression pattern
from initial artery injury through clinically manifest disease


Lists of potential CAD risk factors were discussed for the past 10 years:
These physicians above all have brought up a variety of coronary risk factors which are strong nasty plaque-builders. They did an immense service by listing new variables in the equation for heart disease. In addition, Drs. McCarron and Oparil et al demonstrated in a controlled trial that a comprehensive nutrition program was spectacularly powerful in lowering BP, insulin, glucose, LDL, LDL/HDL ratio, homocysteine and other drivers of heart disease. McCarron DA, Oparil S, et al. Comprehensive nutrition plan improves cardiovascular risk factors in essential hypertension. Am J Hypertens. 1998 Jan;11(1 Pt 1):31-40.



The below publication from 2002 was produced from the AACE , the venerable group of brilliant forward-thinking experts which I mentioned earlier (updated recently in 2006 to take into account the Heart Protection Study and other landmark trials).

The American Association of Clinical Endocrinologists Medical Guidelines for Clinical Practice for the Diagnosis and Treatment of Dyslipidemiaand Prevention of Atherogenesis 2002 (Amended Version)



The first thing that blew me away about these guidelines was the demonstration of the utilization of CT scan scoring is on Table 16 on p.195 for an evaluation of a CAD patient case study (although I believe truly 'normal' is a zero score). Back in 2002 even CT scan results provided value to the AACE as a standard of practice for detecting high risk heart disease and the presence of plaque.



Wow.



Isn’t that interesting? Back in 2002...



This is why I like the AACE…



Personally, in my opinion the pictures also are fantastic . Please see if you're into the pathogenesis of pro-atherogenic lipoproteins:
  • Fig 1, 2, 3 on p.175
  • Fig 4 on p.176
  • Fig 5 on p.180

The AACE also identified the below Risk Factors for Coronary Artery Disease (Table S-1 on pg.166) which enumerate the same ones listed in the above medical journal articles.

Coronary Risk Factors

High total cholesterol or LDL-C

Small, dense LDL

Low HDL-C

Hypertriglyceridemia

Advancing age

Type 2 diabetes mellitus

Hypertension

Obesity

Cigarette smoking

Family history of CAD

Increased levels of Lp(a) lipoprotein

Factors related to blood clotting, including increased levels of fibrinogen and PAI-1

Hyperhomocysteinemia

Certain markers of inflammation, including C-reactive protein

And… this is why I really REALLY like the AACE:

  1. Other risk factors for heart disease were additionally identified -- PCOS, hypothyroidism, SLE/lupus, Cushing's disease, etc (common theme: inflammation, insulin resistance)
  2. A moderate, lower-carb diet is favored over a typically AHA high- carb diet (on p.196; first 1-2 paragraphs) for a patient with elevated triglyerides (which is 50% of all Americans according to the NHANES data, although I'd predict that would probably be about 70% now)
  3. Can the AACE top their already prescient anti-atherogenesis guidelines?? Absolutely... A brief cost-benefit analysis (on p.196 Fig 6) of the resources conserved when cardiac events, surgeries and hospitalizations are successfully averted with lifestyle/medical/nutritional therapy. Does this remind you of Heart Hawk's incredible cost-analysis report ??

The AACE are surprisingly one of the most progressive group of classic, systemic heart disease and prevention experts (btw they are not Cardiologists – wonder why is that?).



So who... can possibly... trump the AACE??



Who seems to be scientifically... divinely inspired...



Dr. Davis certainly seems to possess otherworldy genius. Not only has he assembled the best plan to strategically reduce all plaque growth and eradicate plaque by tackling each and every one of these risk factors identified so far (and then some!), but he has also taken the art of medicine to a practical and do-able level for any person concerned about heart disease. By encouraging discussion, empowerment and pro-activism, the solutions are transparent and T-Y-P-ically reachable.



And the community to fully engage in the TYP program is about to be advanced to the next level... TYP 2.0!



Can you find that elsewhere I must ask?



A brief review of the TYP Strategy:

Plaque-Builders TYP Strategy TYP Goals To Reduce EBT Score
----------- -------------------------- -----------------
Blood pressure L-Arginine, Vitamin D3, exercise, IBW, weight loss, carb restriction, cocoa extracts, etc Normalization: BP = 110/70 Pulse 60
Vitamin D3 Deficiency Supplementation of D3 (cholecalciferol in oil gel capsules) Normalization: 25(OH)D3 = 60 ng/ml
Presence of Small LDL Wheat elimination, carb restriction, Niacin, Vitamin D3, Oat bran, Intermittent Fasting, etc Small LDL less than 10% (LDL less than 60 mg/dl)
Elevated TG Wheat elimination, increased intake good oils/fats, high dose fish oil, Vitamin D3, Vitamin B3 (niacin), etc TG less than 60 mg/dl
Low HDL

See above, strength training, carbohydrate restriction, dietary oils/fats, etc

HDL 60 mg/dl or higher
Lipoprotein(a) See Lp(a) TYP Report , Niacin, Vitamin D3, high dose fish oil, Carb restriction, L-carnitine, coQ10, raw nuts, DHEA, Estrogen, Testosterone, adequate good oils/fat, etc

Normalization: Lp(a) less than 30 mg/dl

Homocysteine Vitamins B6, B12, Folic acid, Wheat elimination, Estrogen, etc Normalization: Homocysteine less than 8.0
Fibrinogen Aspirin, fish oil, raw nuts, carb restriction, exercise, smoking cessation, etc Normalization
Abnl Glucose, Hyperinsulinemia,Type 2 Diabetes, Type 1 Diabetes Wheat elimination, Carb restriction, Exercise, IBW, Vitamin D3, high dose fish oil, raw nuts, Magnesium, Estrogen, etc Normalization: Premeal glucose less than 85 mg/dl; Insulin less than 5-10 uIU/L (A1C 5.0%)
Metabolic syndrome (including Central Obesity, NAFLD, Cardiac Steatosis, PCOS, Acanthosis Nigricans) Same As Above Normalization: ALT, AST less than 40 (Normal Echo)
Estrogen Deficiency Bio-identical HRT, Vitamin D3, etc Normalization
Testosterone Deficiency Replacement, Vitamin D3, etc Normalization
Antioxidant Deficiencies Diet/supplementation of Vitamin K2, C, E, A, D3, etc Normalization
Thyroid Disorder Replacement, Vitamin D3, Magnesium, Calcium, etc Normalization: TSH 0.2 - 2.0 mIU/L
Oxidative Stress, Inflammation Above strategies, exercise training, yoga, meditation, Natural Vitamins, improvement of sleep (quantity, quality), mental stress reduction, high dose Vitamin ‘O’, etc Normalization: CRP less than 3.0
Chronic Kidney Disease BP and glucose normalization, Vitamin D3, high dose fish oil, address Lp(a)/Homocysteine, etc Normalization: Cr less than 0.8-1.0 Microalbuminuria less than 20 ug/mg
Abdominal/Thoracic Aortic Aneurysm, Valvular Disease All the above, BP normalization, Vitamin D3, etc Normalization: Prevention of dissection and expansion
Other CAD Risk Factors Identified under TrackYourPlaque.com See TYP


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