(Normally pre-load , after load , and contractility should be sequentially matching parameters . After load mismatch is an important concept where myocardial contractility is temporarily is depressed due to lack of adequate pre-load for a given level of after load )
Evidence for reversibility
Very often one can observe improvement of LV function significantly 24 hours after dialysis .The concept of uremic biochemical dysfunction is still valid .Though it can not be exactly quantified .
If significant coronary artery disease is excluded , these patients do well ( after transplantation ) from a cardiac point of view !
(64 slice MDCT may be a simple screening test to rule our significant CAD .)
How wise it is to do renal transplantation in DCM patients ? .
Most patients with LV dysfunction of CKD do well after transplantation .
Presence of severe LV dysfunction especially with normal or increased wall thickness should not be a contraindication to renal transplantation .