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Are there any cases where the calcium score is high but heart disease is not present?


Posted by JudyBanks

I have high LDL, but perfect HDL and Triglycerides.  My CRP test showed no inflammation and the stress test was no problem (I am a runner and athlete).  The tests were ordered because of the high LDL numbers, I am symptom free. The problem is that my calcium score was extremely high.  Can you have a high calcium score and NOT have heart disease, or is it always an accurate indicator of heart disease, plaque, blockages?  I am just curious if there are cases of high calcium scores, and yet no heart disease present. Can not seem to find any information on this anywhere.
 
Answers (3)
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Calcium scores are accurate indicators of historical inflammation in the heart arteries and not of active blockage.  At the very least, I would treat your LDL levels to below 70 with statins as an aggressive therapy with the presumption of coronary artery disease.  Admittedly aggressive, but it should drive regression of any active stable coronary artery atheromas if LDL level can reach 50-60's.

Hopefully your stress test included imaging (e.g. nuclear).

Note, many physicians do not believe calcium scores add to clinical decision making and don't order them.

How are the cRP tests and the calcium score test related.  If the crp is very low, indicating no inflammation, shouldn't the calcium score have a similar outcome?
Both are markers of inflammation, but calcium scoring is a marker of historical inflammation, while hsCRP is more a marker of the current inflammatory state.
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