study published early online last week in the European Heart Journal in which the authors concluded that use of cholinesterase inhibitors (ChEI) in those with Alzheimer's disease (AD) was associated w/lower risk of heart attack & death. I don't know about you, but for me, that came out of left field . The authors followed 7,073 Swedes (avg 79yo) w/AD for an average of 503 days (just over a year & 4mo for those of you who think like I do in those terms).But with all that in mind, I must admit that my curiosity was piqued when I stumbled upon a
After taking into account the usual suspects (confounders), the authors noted that those participants w/AD who took a ChEI had a one-third lower risk for heart attack or death compared to those who did not take a ChEI. Similar statistics were noted when ChEI use was compared to heart attacks & deaths in isolation in non-users. More importantly, use of the highest ChEI doses was associated w/lowest risk of heart attack (65% lower) and death (46% lower), again compared to non-users.
So what's this mean for you & me? I dunno! But it's certainly intriguing! And I'm definitely looking forward to that next strand of spaghetti being flung against the wall . . .
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