Recently, research from UT Southwestern led by Dr. Roberto Coppari, showed that when resveratrol was directly injected into rats fed a high caloric and fat laden diet showed a decrease in insulin level while those on the placebo injection actually showed an increase. This research was different than the research we have seen in the past because in this study the resveratrol was injected directly into the brain. Researchers in this study felt there was not enough evidence to suggest that oral consumption of resveratrol from red wine or supplements would deliver the same effect because the resveratrol does not pass from the blood stream into the brain.
This new research provides direction for further research and for companies looking to create resveratrol based drugs to battle diseases of aging, such as Sirtris Pharmaceuticals and Elixir Pharmaceuticals . They can now focus on finding ways to get the resveratrol to pass from the blood stream into the brain. The study authors further claim that these findings also show that resveratrol activates sirtuins in the brain which may also be responsible for the calorie restriction mimetic effect of resveratrol.
We are still a long way from knowing exactly how and why resveratrol works and if this can be replicated in humans. The good news is there are highly reputable Doctors and Researchers currently working on figuring out how to increase our lifespan while living healthier at the same time.
Recently, research from UT Southwestern led by Dr. Roberto Coppari, showed that when resveratrol was directly injected into rats fed a high caloric and fat laden diet showed a decrease in insulin level while
those on the placebo injection actually showed an increase. This research was different than the research we have seen in the past because in this study the resveratrol was injected directly into the brain. Researchers in this study felt there was not enough evidence to suggest that oral consumption of resveratrol from red wine or supplements would deliver the same effect because the resveratrol does not pass from the blood stream into the brain.
This new research provides direction for further research and for companies looking to create resveratrol based drugs to battle diseases of aging, such as Sirtris Pharmaceuticals and Elixir Pharmaceuticals . They can now focus on finding ways to get the resveratrol to pass from the blood stream into the brain. The study authors further claim that these findings also show that resveratrol activates sirtuins in the brain which may also be responsible for the calorie restriction mimetic effect of resveratrol.
We are still a long way from knowing exactly how and why resveratrol works and if this can be replicated in humans. The good news is there are highly reputable Doctors and Researchers currently working on figuring out how to increase our lifespan while living healthier at the same time.