Resveratrol and Related Compounds Questioned over SIRT1 Activation
Posted Apr 02 2010 10:19am
In the anti-ageing research world, there is a quiet but albeit, an important battle brewing. The battle is over whether or not resveratrol and compounds similar to it, such as SRT1720, actually do directly activate SiRT1.
The implications of such findings would have a great impact on companies developing anti-aging drugs or therapies associated with the SiRT1 gene. It will be interesting to see where the research takes us.
I have gathered some links for those of you interested in reading more on the topic:
Faculty of 1000 Biology: evaluations for Pacholec M et al J Biol Chem 2010 Mar 12 285 (11) :8340-51
Nature News: Published online 24 March 2010 | Nature 464, 480-481 (2010) | doi:10.1038/464480a
Doubts grow over resveratrol and other compounds under development at the GSK company.
Technology Review, Published by MIT Author: Emily Singer
In the anti-ageing research world, there is a quiet but albeit, an important battle brewing. The battle is over whether or not resveratrol and compounds similar to it, such as SRT1720, actually do directly activate SiRT1.
The implications of such findings would have a great impact on companies developing anti-aging drugs or therapies associated with the SiRT1 gene. It will be interesting to see where the research takes us.
I have gathered some links for those of you interested in reading more on the topic:
Faculty of 1000 Biology: evaluations for Pacholec M et al J Biol Chem 2010 Mar 12 285 (11) :8340-51
Nature News: Published online 24 March 2010 | Nature 464, 480-481 (2010) | doi:10.1038/464480a
Doubts grow over resveratrol and other compounds under development at the GSK company.
Technology Review, Published by MIT Author: Emily Singer