a. Sulphonylureas act by sensitising beta cell to the action of glucose
increase insulin receptors.
Eg. Chlorpropamide
Tolbutamide
Glibenclamide
Glipizide

b. Biguanides . act by reducing hepatic gluconeogenesis and Increasing peripheral utilization of glucose
Useful in obese diabetics
Danger of lactic acidosis with phenformin
C.Others:repaglinide,acarbose,troglitazone