Why the difference? This time, the authors analyzed data from 9 studies comprised of 16,701 participants regarding effectiveness and 16,611 regarding safety when used for treatment of acute venous thromboembolism and prevention of same. In fact, use of rivaroxaban was associated with lower risk of bleeding.
Bottom line: assuming one survives the wallet biopsy, these new oral anticoagulants are safe for use in treating DVT but not in preventing same in the immediate post-ACS period of time while taking an anti-platelet agent, too. Ah, the devil is in the details.
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