JAMA Pediatrics in which the authors reviewed the literature looking at how to treat children & adolescents with headaches, especially migraines. In the first review , the authors concluded that only topirimate & trazodone might have limited evidence supporting its use in children & adolescents suffering from migraines. However, all other commonly used medications in adults lack any supportive data.So of course I read w/interest 2 studies published online earlier this week in
In the second review , ostensibly a comparison of the various triptans available for use in adolescents, the authors were only able to conclude that 53-57% of migraine patients responded to placebo. Given such a tremendous response rate, it's near impossible to prove efficacy of triptans in adolescents.
So while children & adolescents w/newly diagnosed diabetes may respond similarly to adult-based therapies, such is not the case in those w/migraines. Those children & adolescents suffering from headaches need to be treated as children & adolescents, not little adults. Much research needs to be performed in order to determine how best to help this population subset.