Younger adults do get this type of cancer, but as you age, those risks increase. More than 90 percent of the people diagnosed are over the age of 50. If you have a history of colorectal polyps, colorectal cancer, if your polyps are large or if you have had a lot of them, your at an increased risk. Even if you have all the polyps removed, the chances of developing new cancers in other parts of the colon or rectum are greater.
Sporadic colon tumors are caused by somatic mutations in a few critical genes that accumulate in a single cell lineage. Hereditary colon tumor syndromes are caused by mutations in the same genes that cause sporadic tumors, but at least one of these is an inherited or germline mutation. Because the first mutational step has already occurred in every cell at the time of birth in the hereditary case, only one additional somatic mutation affecting a single cell is sufficient to inactivate that gene function. In contrast, sporadic cases require two distinct somatic mutational events to inactivate both the maternal and paternal copies of these genes in the same cell before a tumor develops.
Counseling regarding the possible risks and benefits of cancer early detection and prevention modalities and a discussion of the basic elements of informed consent should be obtained before offering germline DNA testing. Counseling should help the patient and family know the information provided, help them feel comfortable in the process of making an informed choice, and support them in choosing a course of action regarding management of their cancer risk and aid their psychosocial adjustment to the knowledge gained. The American Society of Clinical Oncology has recommended cancer predisposition testing if all these criteria are met the prior probability of a positive result is high, because the patient has a strong family history of or very early onset of disease. In addition, the test can be adequately interpreted. Finally the results will influence the medical management of the patient or family.
Research suggests one of the best ways to prevent colon cancer is to eat right. An Ohio State University study found that rodents who were fed raspberries with their meals developed 80% less tumors than rodents who ate regular food. Blackberries and raspberries contain anthocyanins and polyphenolics, which inhibit blood vessel formation that would normally feed a cancerous cell. Secondly, an 8-year study from UCSD found that vitamin D/sunlight exposure alters the growth of colon cells to prevent malignancy. It’s best to spend 10 minutes in the sun before applying sunscreen, as even SPF-8 lotion can reduce your ability to convert sunlight to Vitamin D by 95%. A University of Maryland lab study shows that the inositol hexaphosphate (IP6) fiber in corn prevents the growth of the colon cell by regulating cell activity. Louisiana State University researchers learned that curry inhibits cancer cell movement and can even ruin some smaller cancer cells. Lastly, Oregon State University researchers recommend white tea for its anti-oxidant properties. In addition to these foods, individuals should limit red meat, saturated stout , alcohol and tobacco consumption You can be published without charge. You can to republish this article in your website or blog. Please provide links Active.