Grapefruit pulp reduce brittle bone disease in the body
Posted Nov 30 2008 12:00am
According to a recent research work that was carred out by researchers from Texas A&M University and published in the journal Nutrition. it was discovered that consumption of red grapefruit pulp may increase bone strength and reduce the risk of osteoporosis “brittle bone disease”
Researchers castrated 42 male rats as a way to induce oxidative stress and to increase the risk of osteoporosis. 1/3 of the rats were then fed a normal diet, 1/3 were fed the same diet plus five per cent red
grapefruit pulp, while the final third were fed the same diet plus 10 per cent red grapefruit pulp.
After 60 days of the experiment, the castrated rats on the normal diet showed significant decreases in antioxidant status, bone mineral content and bone quality when compared with 14 uncastrated male rats. They also demonstrated increased calcium loss and higher levels of urinary deoxypyridinoline, a marker of bone breakdown. Decreased bone mineral content and bone quality are markers of a heightened risk of osteoporosis, as are increased calcium loss and higher urinary deoxypyridinoline concentrations.
Among the castrated rats whose diet was supplemented with grapefruit, urinary deoxypyridinoline levels were lower than in the other castrated rats. While all the castrated rats underwent decreases in the magnesium and calcium content of their bones, this decrease was not as severe among the rats in the grapefruit pulp group.
Among the castrated rats not fed grapefruit pulp, lumbar calcium and magnesium levels decreased 16% and
24%, respectively. Among the rats in the experimental group, however, the respective decreases were only
10% and 16%. Likewise, femoral calcium and magnesium levels dropped by seven percent each among the
non-grapefruit group, but only one percent and three percent, respectively, in the grapefruit pulp groups. The effects of grapefruit pulp were found to be dose-dependent.