With that thought in mind, a meta-analysis of 8 prospective studies was published last month in the British Medical Journal in which the authors concluded that coronary artery calcium score ≥10 is useful in separating the truly high risk from the merely moderate risk. The authors arrived at their conclusion by following 6,521 participants w/T2DM for 5+yrs. Compared to those w/CAC <10, those w/greater scores had five-fold greater relative risk of all-cause mortality & cardiovascular events. So while I am not a great fan of excess radiation exposure, it would appear that imaging might aid in determining who should truly aim for the optional goal LDL of <70mg/dL.
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