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You Ask, I Answer: Essential Amino Acids

Posted Mar 16 2010 10:01pm

methionineAre there eight or nine essential amino acids?

Some books say eight, others say nine.  Both are reliable sources, so I don’t know what’s right.

Some websites even mention there being ten essential amino acids.

– Richard (Last name withheld)
New York, NY

Wonderful question.  There does appear to be quite a bit of confusion on this issue.

There are eight truly essential amino acids:

  • Isoleucine
  • Leucine
  • Lysine
  • Methionine (chemistry fans: its structure is pictured alongside this post)
  • Phenylalanine
  • Threonine
  • Tryptophan
  • Valine

There are four “conditionally essential” amino acids:

  • Arginine
  • Cysteine
  • Histidine
  • Tyrosine

Some people erroneously consider one or two of them essential (which is where figures or “nine” or “ten” essential amino acids come from).

Arginine and histidine are conditionally essential because they are only essential for infants.

Tyrosine is produced from phenylalanine, an essential amino acid.  People with phenylketoneuria (PKU) must strictly restrict their phenylalanine intake, thereby making tyrosine an essential amino acid.

Cysteine is produced from the essential amino acid methionine.  Therefore, some people argue that cysteine is “conditionally essential”, since a diet lacking methionine is also void of cysteine.

Essential amino acid insufficiency is extremely rare in developed nations.  Even in developing nations, it’s only really seen it with populations that do not eat animal products largely subsist on one crop.

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