The family genes seem to play a significant role in cardiovascular longevity.
* Explain to interested patients that the basis of this study was an observational study of white middle-class volunteers, so the results may not be generalizable.
Middle-age volunteers whose parents survived to age 85 or older had significantly better Framingham risk scores than those whose parents died younger, suggesting that cardiovascular longevity may carry a genetic component, researchers here reported.
Compared with those whose parents died younger, offspring of long-lived parents were less likely to be smokers, had lower blood pressure, and a more favorable HDL to total cholesterol ratio, Dellara F. Terry, M.D., M.P.H., of the Framingham Heart Study reported in the March 13 issue of Archives of Internal Medicine.
Dr. Terry and colleagues of Boston University and the National Heart, Lung and Blood Institute said this was the first study to examine "cardiovascular risk factors in the offspring of longer-lived individuals using independent and validated measurements of cardiovascular risk factors."
In the study of 1,697 Framingham Heart Study offspring members ages 30 or older, there was a dose-response relation between parental longevity and Framingham Risk Score, they said.