We are beginning to see more “inhalable” drugs coming on the scene and this is one more that was a small trial, for kids it sure beats having shots and they found that it was well tolerated. One more potential drug to be delivered through that Bluetooth inhaler, maybe? BD
A multi-center clinical trial led by a Riley Hospital for Children endocrinologist has found that inhaled growth hormone (GH) is well tolerated by children with GH deficiency and that this easy-to-use method can, over a one-week period, safely deliver GH to the blood stream. In addition to having implications for those who need GH, this first pediatric study of administering it through the lungs may also help researchers interested in using this convenient method for effectively delivering other types of medications to children.
Results of the study appear in the June 2009 issue of the Journal of Clinical Endocrinology & Metabolism.
“We need to find less painful ways of administering drugs to children and we were pleased to see that inhaling GH raised the levels of two important indicators in the blood in these children for whom GH was prescribed for growth hormone deficiency or multiple pituitary hormone deficiencies,” said Emily Walvoord, M.D., associate professor of clinical pediatrics at the Indiana University School of Medicine, who is the Riley Hospital physician coordinating investigator of the five-center study of 22 patients.