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Clinical Trials to Begin for Malaria Vaccine Later This Year

Posted Sep 05 2010 12:46pm

This is something that is needed like now.  I also posted about a movie that is coming out that discusses DDT and the desire to bring the chemical back and discussed the potential dangers and non dangers associated along with the decision to stop DDT back in the Nixon administration.

Malaria and the cure has also been a big focus for the Bill and Melinda Gates Foundation.

Bill Gates - an optimist and a comedian – Fills the Room with Mosquitoes at TED

After some very extensive research  NITD609 was identified as a potential drug candidate. Plasmodium falciparum and Plasmodium vivax have been conquered the drug resistant strain of malaria we are seeing today.  Genomics research from the Scripps Research Institute played a major role in this investigation.

Scripps, Navigenics, Affymetrix and Microsoft team on groundbreaking health study – Personalized Medicine

A little information from the recent past above with Scripps using various clip_image002 technologies with genomics to include HealthVault personal health records to store a lot of their information derived from studies too.  BD 

An international team of scientists plans to begin clinical trials for a new malaria vaccine later this year.
Researchers from The Scripps Research Institute, the Swiss Tropical Institute, the Genomics Institute of the Novartis Research Foundation and the Novartis Institute for Tropical Diseases revealed their findings in the September 3 issue of the journal Science, according to
Elizabeth Winzeler, a Scripps Research associate professor and member of the Genomics Institute of the Novartis Research Foundation, told that she was excited by the new compound. image

After initially finding 275 potential candidates, Winzeler was able to narrow the field to just 17 that could be effective and safe for humans. After looking at the toxicity and pharmacokinetic profiles of those, one compound stood out as promising. It belonged to a chemical class of molecules known as spiroindolones. Spiroindolones had never before been associated with malaria.

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