Women with High FSH And High AMH Are Twice as Likely To Have Success With IVF
Posted Aug 05 2013 12:00am
Over the past couple of months I’ve been listening
into Fertility Insights, a live webcast series run by Center for Human
Reproduction, a fertility clinic in New York.
It’s a program where fertility doctors and
researchers from the Center for Human Reproduction (or CHR) discuss fertility
research that affects and interests everyday men and women who struggle with
infertility. The webcast is a breath of
fresh air because it covers scientific studies by relating them to issues that
real couples and individuals with infertility face.
Their first episode concentrated on discussing
recent research that examined the relationship between two blood tests that every women who’s been through
infertility treatment is probably familiar with:
Sufferers of diminished ovarian reserve (or DOA) probably
know the high FSH/low AMH combination, which indicates that ovarian function
isn’t in optimal health. DOA means that pregnancy chances without fertility
treatment are low.
Though this high FSH/low AMH combination is one of the
most common presentations amongst women with DOA, AMH and FSH levels can be abnormal in other patterns – such
as high FSH and high AMH. This
combination is somewhat unusual, and the researchers from CHR took a look at
what it means to have hormone levels like this.
CHR’s researchers found that during IVF, these women
had 4 times as many eggs retrieved and were nearly twice as likely to get
pregnant after IVF. This is compared to
women with other FSH/AMH combinations.
Although they recognized that this group
of women represents a very small percentage of women with infertility, it’s
still great news! Specialists are closer to understanding why having a high FSH
may not be terrible news for your fertility, if coupled with other factors, such
as (in this particular study) a high AMH.
The study’s results also highlights
the importance of not just looking at FSH levels when assessing a woman’s ovarian
reserve – your specialist should also measure other hormonal blood tests, such
as AMH, and interpret the different levels in relation to each other.
You can find the full study details and results in
the Journal of the Endocrine Society . But if I were you and wanted to
learn more, I’d just check out the webcast. It’s easier to digest for the
non-medically trained and it’s followed by some pretty interesting Q&A
session between Dr. Norbert Gleicher, the study’s head researcher, and some actual
patients. Here’s a recording of the webcast. The audio has an
echo for the first 4 minutes, but after that it clears up.