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User-friendly, Powerful Software for Analyzing ChIP-Seq Data

Posted Apr 22 2013 8:00pm

Description of Invention:
The present invention provides a user-friendly software, called PAPST (Peak Assignment and Profile Search Tool for ChIP-Seq), for bench scientists to work with ChIP-Seq data in seconds, allowing the scientists to screen genes against multiple genomic features with ease and efficiency previously not realized. Furthermore, PAPST may be used to identify genes of special significance in a wide variety of biological and biomedical fields, which could lead the discovery of disease-associated genes and the development of therapeutic methods for human diseases. Lastly, this powerful, easy-to-use software does not require any special computation expertise.

Applications:
  • Genomic analysis.
  • Drug target identification.


Advantages:
  • Easy to use.
  • Fast.
  • Either a stand-alone software or as an add-on to existing commercial software.


Development Status:
  • Prototype
  • Pilot


Inventors:
Paul W Bible (NIAMS)
Hong W Sun (NIAMS)
Lai Wei (NEI)
Yuka Kanno (NIAMS)


Patent Status:
HHS, Reference No. E-008-2012/0

Research Tool – Patent protection is not being pursued for this technology.

Relevant Publication:
  1. Yang XP, et al. [ PMID 21278738 ]
  2. Yamane A, et al. [ PMID 21113164 ]
  3. Ghoreschi K, et al. [ PMID 20962846 ]


Collaborative Research Opportunity:
The Biodata Mining & Discovery Section of the National Institute of Arthritis and Musculoskeletal and Skin Diseases is seeking statements of capability or interest from parties interested in collaborative research to further develop, evaluate or commercialize PAPST (Peak Assignment and Profile Search Tool for ChIP-Seq). For collaboration opportunities, please contact Hong-Wei Sun at 301-496-0016 or sunh1@mail.nih.gov .


For Licensing Information Please Contact:
Michael Shmilovich Esq.
NIH Office of Technology Transfer
6011 Executive Blvd. Suite 325,
Rockville, MD 20852
United States
Email: shmilovm@mail.nih.gov
Phone: 301-435-5019
Fax: 301-402-0220


Ref No: 2557

Updated: 04/2013

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