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The Effective Treatment of Osteoporosis with Oestrogen Hormone

Posted Aug 31 2013 11:19am

Effective treatment of Osteoporosis with Oestrogens

Professor John Studd

Editors foreword

Professor John Studd is generally regarded as the leading light in the campaign for women’s medicine and healthcare. He was awarded the Gold Medal of the Royal Society of Medicine for the obstetrician/gynaecologist who has made the greatest lifetime contribution to women's health. He has fought the medical cause on behalf of women and has been proved consistently correct in his views on the important role of hormoneA substance produced by a gland in one part of the body and carried by the blood to the organs or tissues where it has an effect. therapy. He says that both doctors and patients need to be aware that HRTAbbreviation for hormone replacement therapy, the administration of female hormones in cases where they are not sufficiently produced by the body. should be the frontline treatment and that women are best cared for by the appropriate experts i.e. gynaecologists. Oestrogens are proved to be the best treatment to prevent the symptoms of menopauseThe time of a woman’s life when her ovaries stop releasing an egg (ovum) on a monthly cycle., not to mention the horror of spine fractures associated with osteoporosisA condition resulting in brittle bones due to loss of bony tissue.. In the meantime big pharma has stepped in to fill the treatment void caused by the discredited 2002 WHI Study with their own alternative products such as the bisphophonates and antidepressants (see - Profox nightmare) and the danger is that these drugs can do more harm than good.

The Royal College of Obstetricians and Gyneacologists website states:

“The effects of HRT have been studied in over a million women worldwide and research shows that for most women HRT works and is safe.”

 

Why Women can now Benefit from Oestrogen Treatment

“Hormone therapy is the most logical and the most beneficial treatment for low bone density”.

 

HRT - Altered Opinions

About 20 years ago Hormone Replacement Therapy (HRT) was the only really effective treatment for osteoporosis. However, following the bad news from the 2002 WHI study, oestrogens were subsequently considered not to be the first choice of therapy. Fortunately for women this study has now been totally discredited and retracted even by the investigators. As a result of the WHI study most physicians who are virtually always poorly trained in hormone therapy happily resorted to the use of bisphosphonatesA family of drugs that prevent the break down of bone by cells called osteoclasts., strontium, parathyroid hormone or worse.  These treatments may be appropriate for the older patient but for the younger woman on long term therapy there are major side effects including epigastric pain, osteonecrosis of the jaw, femoralRelating to the area at the top of the thigh, near the top of the femur (thigh bone). mid-shaft fractures and there is also a suggestion of an increase in oesophageal cancerAbnormal, uncontrolled cell division resulting in a malignant tumour that may invade surrounding tissues or spread to distant parts of the body..

The evidence is now clear that the safest and most effective way to increase bone density in women under the age of 60 years is by treatment with oestrogens.  The denial of oestrogens to these younger women is tragic when we consider the many younger 30-40 year old women with premature menopauseThe time when a woman's periods permanently cease. or with a history of anorexiaA loss of appetite resulting in weight loss. Anorexia nervosa is a psychological illness in which self-starvation leads to weight loss. and amenorrhea.

 

Thin Women Deficient in Oestrogen

Thin women including those with an exercise and / or marathon running addiction, or healthy thin women who consider walking the dog for 2 hours a day sufficient exercise may also be deficient in oestrogen.  For these women, the oestrogen deficiency could be due to premature ovarianrelating to the ovaries failure or amenorrhea or simply because they are thin and not producing sufficient oestradiol in their own body fatOne of the three main food constituents (with carbohydrate and protein), and the main form in which energy is stored in the body.. In these cases transdermal oestrogens must be regarded as the correct first choice of treatment.  Similarly premenopausal women are at risk if they have a hysterectomyThe surgical removal of the uterus (womb). and bilateralOn both sides of the body oophorectomy without appropriate hormone replacement. These women clearly need oestrogen's to treat the post oophorectomy symptoms as well as for protection of the skeleton.

 

Oestrogen Treatment Anabolic for Skin and Spine

There is a decrease in skin collagen sssociated with ovarian failure regardless of age due to lack of oestrogen. Oestrogen therapy will replace the missing hormone and improve the quality of skin thickness and skin elasticity.  Equally the loss of collagen also happens in the bone matrix, which is the vital scaffolding and structure of the bone.  Oestrogen replaces the missing collagen in the matrix of osteopenic bone. This same anabolic effect upon the collagen protects the intervertebral discs in the spine. The discs make up one quarter of the length of the spinal column and serve as a cushion protecting your spine and preventing the development of vertebral crush fractures. This is why osteopenia or, of course, osteoporosis are major causes of spine fractures. Oestrogens protect the intervertebral discs and bisphosphonatesA class of drugs used in osteoporosis and other bone diseases to reduce loss of bone mass do not.

 

A Generation to dispel the old HRT Myths

“The most beneficial treatment for low bone density”

Any anxiety about the safety of HRT should have disappeared by now. However, a major problem remains in that the spurious ‘side effect’ of HRT in women is now in the undergraduate textbooks and it will take a generation to get rid of this misinformation.  Women may also have regular or even troublesome periods or may develop breast discomfort on HRT.  These are relatively minor problems that a gynaecologist can deal with. The problem is that these symptoms are outside of the training of bone physicians and so these doctors will continue to be reluctant to use the most logical and the most beneficial treatment for low bone density.

All the latest information indicates that HRT is safe and is associated with the removal of most of the climacteric symptoms including loss of libidoSexual drive. and depressionFeelings of sadness, hopelessness and a loss of interest in life, combined with a sense of reduced emotional well-being as well as the more obvious hot flushes and sweats. 

 

Oestrogen Skin Patches Preferred

It is safer to use transdermal oestrogens as this route does not stimulate coagulation factorsA group of substances that can undergo a cascade of reactions in certain conditions, leading to the coagulation of blood. Also known as clotting factors. from the liverA large abdominal organ that has many important roles including the production of bile and clotting factors, detoxification, and the metabolism of proteins, carbohydrates and fats. and does not encourage deep vein thrombosisObstruction of one of the deep veins, often in the calf, by a blood clot. Often abbreviated to DVT. (DVTAn abbreviation for deep vein thrombosis: the obstruction of one of the deep veins, often in the calf, by a blood clot.), strokeAny sudden neurological problem caused by a bleed or a clot in a blood vessel. or pulmonary emboli. It does seem that the risk factor in HRT is more with the cyclical or continuous progestogen.  Following hysterectomy women can have oestrogens probably with the addition of testosteroneThe main male sex hormone. without progestogen and data now from two large studies confirm that this is associated with less breast cancer and fewer heart attacks and cardiacRelating to the heart deaths.

 

Women should not be denied this effective treatment

There seems no reason to deny women particularly under the age of 50 years relief of symptoms and protection of osteoporosis by denying them the transdermal oestrogens.  It seems that this is an important lesson that many physicians have yet to learn.

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