Sadly over 20% of Women in their 40's and 50's in US on Anti-Depressants
Posted Sep 06 2013 9:51am
It is estimated that over twenty per cent of wmoen in their forties and fifties in the US are being prescribed antidepressant drugs. Possibly a small consolation for these women is a recent study that says, "initiating pharmacological therapy always requires careful balance of potential risks and benefits of the treatment, results suggest that SSRIs and tricyclic antidepressants do not appear to have adverse effectsUndesirable side-effects of medication. on BMD in women".
One somewhat dubious justification for prescribing antidepressant drugs in menopausalRelating to the menopause, the time of a woman’s life when her ovaries stop releasing an egg (ovum) on a monthly cycle. women is that limited studies (with conflicting outcomes) show serotonin receptors present in the cells responsible for bone metabolismThe chemical reactions necessary to sustain life.. However, even if this observation is confirmed it does not mean that serotonin-based, or other antidepressant drugs will promote bone growth, infact the oposite effect is equally possible.
According to researchers in the Journal of Clinical Endocrinology and Metabolism antidepressants have no effect on bone loss, so that is at least good news for at least 20% of women in the US in their forties and fifties. But it raises the obvious question - why are they on antidepressants anyway when oestrogenA hormone involved in female sexual development, produced by the ovaries. is the preferred frontline treatment? Depression has previously been shown to have an affect on bone loss and increased risk of fracture, but this does not mean that prescribing antidepressants is the solution. The underlying cause of bone loss, depressionFeelings of sadness, hopelessness and a loss of interest in life, combined with a sense of reduced emotional well-being and other symptoms of menopauseThe time of a woman’s life when her ovaries stop releasing an egg (ovum) on a monthly cycle. is falling oestrogen levels. Low bone density is more common in women with depression, the underlying cause of the depression is reduced oestrogen and this is the reason why it is important to treat women with transdermal oestrogen and not antidepressants and / or other bone drugs,
This subject is already covered by the PROFOX article by Professor Studd. In this article John Studd describes the nightmare scenario of treating women with a combination of antidepressants (Prozac) and Fosamax (Bisphosphonates).