Multiple Donor Tissue-Derived Large IgM VH-Based Fab Human Antibody Library
Posted Jul 30 2012 8:00pm
Description of Invention: Available for licensing as a biological material for either internal use or commercial distribution is a human Fab immunoglobulin/antibody fragment phage display library. The library contains 1010 Fabs derived from the peripheral blood of ten (10) healthy human donors. The high quality of the library was demonstrated in the successful selection of high affinity antibodies specific for Hendra and Nipah viruses; however, the library is useful for selecting a variety of antigen specific immunoglobulin/antibody Fab fragments especially for cancer or viruses.
Applications: Antibody discovery – Diagnostics, Therapeutics, Research Reagents
Advantages: High affinity multi-purpose antibodies
Collaborative Research Opportunity: The NCI is seeking statements of capability or interest from parties interested in collaborative research to further develop, evaluate, or commercialize therapeutic, diagnostic or research reagent antibodies. Please contact John Hewes, Ph.D. at firstname.lastname@example.org for more information.
For Licensing Information Please Contact: Michael Shmilovich Esq. NIH Office of Technology Transfer 6011 Executive Blvd. Suite 325, Rockville, MD 20852 United States Email: email@example.com Phone: 301-435-5019 Fax: 301-402-0220