Health knowledge made personal
Join this community!
› Share page:
Search posts:

Gynaecomastia (the large male breast)

Posted Apr 05 2012 5:23am 1 Comment

This article describes the common condition of male breasts also known as gynaecomastia. This will be of help to any man who may be suffering from gynaecomastia and would like to know whether to go ahead with treatment.

Gynaecomastia, in simple terms means abnormally large breasts on men and derives from the Greek ‘gyne’ meaning women and ‘mastos’ meaning breasts. The condition is relatively common and affects approximately 40% of men. Gynaecomastia, also known as man boobs or ‘moobs’ can cause feelings of shame, self-hate, inadequacy and sufficient embarrassment to interfere with a patient's social life.

Gynaecomastia (pre-surgery)

Idiopathic gynaecomastia, is spontaneous and the cause is unknown. This is the most common type of gynaecomastia, of which the majority of cases are due to puberty.


Approximately half of all adolescent boys will experience gynaecomastia as the breast buds develop due to changing hormones during puberty. This can be due to a lack of androgenA type of steroid hormone that stimulates male development. Testosterone is an androgen., or an overabundance of oestrogenA hormone involved in female sexual development, produced by the ovaries.. This will normally be temporary, becoming most prevalent around the age of 14 and will resolve by itself, not requiring treatment.

It is thought that about 20% of cases of gynaecomastia are a result of chemicals or hormones found in drugs taken either for either medical or recreational reasons.

Recreational drugs


Anabolic steroids typically used by body builders can cause glandular gynaecomastia whereby the tissueA group of cells with a similar structure and a specialised function. underneath and surrounding the nipple becomes concentrated and enlarged causing the appearance of a ‘puffy nipple’. This results from the excess levels of testosteroneThe main male sex hormone. found in the steroids which, when converted to oestrogen, will cause breast growth.

Medical drugs

Gynaecomastia has been associated with medications such as anti-depressants, anti-psychotics, oestrogens (for prostateA gland that surrounds the urethra near the bladder. It produces a fluid that forms part of the semen. cancerAbnormal, uncontrolled cell division resulting in a malignant tumour that may invade surrounding tissues or spread to distant parts of the body.), cimetidine (for heart burn and peptic ulcers), digoxinA drug used to treat heart failure or rhythm disorders. (for heart flutters) and spironolactone (for heart failureFailure of the heart to pump adequately.).

Recreational drugs

Social drugs such as alcohol, amphetamines, heroin and marijuana have been found to correlate with gynaecomastia although there is disputed evidence as to whether they can cause the condition. When a patient is seen by the consultant, a thorough history is taken and asks about past and present drug use.

Gynaecomastia occurring as a result of obesity is a result of an excess of adipose tissue. Fat on the chest giving the appearance of breasts without growth of the glandular tissue is known as pseudogynaecomastia and is therefore closely related to exercise and diet.

As the liver is responsible for detoxification, biochemical production and hormone production, any problems with the liver will lead to a disturbance of these factors. The hormones involved in problems with the liver, as well as the medication for cirrhosisscarring of the liver. of the liver are known to cause gynaecomastia. Cirrhosis of the liver will lead to increased oestrogen production which, in turn, can increase growth of the breast tissues.

Similarly to the liver, when there are problems with the thyroid gland this leads to an excess of certain hormones which can lead to breast growth in men.

During kidney disease, the hormonal balance in the body is disrupted which, as in hyperthyroidism or liver disease, can lead to gynaecomastia. About 50% of people suffering from kidney failure and receiving haemodialysisA treatment for renal failure in which the blood is filtered outside the body to remove toxic substances that would normally be processed by the kidneys will experience the condition.

Klinefelter syndrome is a geneticRelating to the genes, the basic units of genetic material. condition whereby a man is born with at least one extra X chromosomeStructures in the cell nucleus that carry genetic information. (normal males have one X and one Y chromosome). Approximately one in every 500–800 males are born with the condition which is signified by low testosterones resulting in small testiclesThe two male sex organs, which sit in the scrotum, and produce sperm and testosterone. at puberty and infertility. Around a third of men with Klinefelter syndrome will also suffer from gynaecomastia.

    Genetics Cancer of the breast and testicles (this is rare) Testicular insufficiency

Surgery for gynaecomastia showing the small incision

The patient should be seen by a breast specialist in order to identify the potential cause and exclude sinister conditions such as breast and testicularRelating to the testicles. cancer.

Gynaecomastia in teenage boys tends to resolve by itself in around 90% of cases over a one–two year period.

If the condition is causing sufficient embarrassment to interfere with the patient's social life, then the cause if identified should be removed or the underlying medical condition should be treated.

Painful gynaecomastia may be treated successfully with tamoxifen (10 mg per day), an antagonist of the oestrogen receptor responsible for the growth of cancerousMalignant, a tumour that may invade surrounding tissues or spread to distant parts of the body. cells.

Drug-induced gynecomastia resolves when the drug causing the condition is stopped, similarly, pseudogynaecomastia can be limited by controlling diet and increasing exercise.

Gynaecomastia (post-surgery)

Surgical correction remains the most effective treatment of symptomatic gynaecomastia. The best surgical technique involves a combination of surgical excisionThe removal of a piece of tissue or an organ from the body. of the glandular component and liposuction of the fatty component using small incisions around the areolaThe small area of darkened skin surrounding the nipple of the breast below the nipple leading to an almost invisible scar. The excessive skin tends to shrink over time. I recommend the avoidance (if possible) of techniques which involve removal of excessive skin and free transfer of nipples in view of the inferior cosmetic results associated with these techniques.

Liposuction alone (under local anaesthesia and sedation) is effective for pseudogynaecomastia (gynaecomastia due to excessive fatty tissue in the breasts).

The patient is usually seen once in the clinic for a wound review after the operation. Some patients develop fluid accumulation at the site of surgery called seroma; this is usually self-limiting but may require fine needle aspirationThe withdrawal of fluid or cells from the body by suction.. Some patients may require psychological counselling.

Comments (1)
Sort by: Newest first | Oldest first
Gynaecomastia will not happen because of over weight. Gynaecomastia happens because of hormonal imbalance. If your age is below 20, You will get different medicines for Gynaecomastia. Once you cross 20, medicines wont be able to cure this. Surgery will be the only option. Ensure to select experienced plastic surgeons for Gynaecomastia surgery. You can reach some good surgeons through this site
Post a comment
Write a comment:

Related Searches