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Device for Non-Surgical Tricuspid Valve Annuloplasty

Posted Apr 22 2013 8:00pm

Description of Invention:
This is a non-surgical tricuspid annuloplasty to treat functional tricuspid valve regurgitation, meaning regurgitation with intact valve leaflets. The device is delivered using novel catheter techniques into the pericardial space and positioned along the atrioventricular groove. A compression member is positioned along the tricuspid annular free wall and tension applied through a variably-applied tension element. In the best embodiment, the compression member has an M shaped portion with at least two inflection points between the segments of difference curvatures.

  • Valvular heart disease
  • Tricuspid valve annuloplasty

  • Non-surgical catheter treatment of valve disease
  • Tricuspid valve

Development Status:
  • Prototype
  • Pre-clinical
  • In vitro data available
  • In vivo data available (animal)

Robert J Lederman (NHLBI)
Toby Rogers (NHLBI)
Kanishka Ratnayaka (NHLBI)

Patent Status:
HHS, Reference No. E-027-2013/0
US, Application No. 61/785,652 filed 14 Mar 2013

Related Technologies:
US, Application No. 13/824,198 filed 15 Mar 2013, Reference No. E-108-2010/0
US, Patent No. 8,211,171, Issued 03 Jul 2012, Reference No. E-249-2006/2
US, Application No. 13/468,761 filed 10 May 2012, Reference No. E-249-2006/2
PCT, Application No. PCT/US2007/023876 filed 13 Nov 2007, Reference No. E-249-2006/2
US, Application No. 61/383,061 filed 15 Sep 2010, Reference No. E-108-2010/0
PCT, Application No. PCT/US2011/51748 filed 15 Sep 2011, Reference No. E-108-2010/0

Collaborative Research Opportunity:
The NHLBI is seeking statements of capability or interest from parties interested in collaborative research to further develop, evaluate or commercialize technologies for functional tricuspid valve regurgitation. For collaboration opportunities, please contact Peg Koelble at .

For Licensing Information Please Contact:
Michael Shmilovich Esq.
NIH Office of Technology Transfer
6011 Executive Blvd. Suite 325,
Rockville, MD 20852
United States
Phone: 301-435-5019
Fax: 301-402-0220

Ref No: 2555

Updated: 04/2013

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