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Aarkstore enterprise---Cell-Based Assays for Drug Discovery

Posted Oct 27 2010 12:48am

   

Table of Contents :

 1. Overview 4
 1.1 Objectives of the Report 4
 1.2 Methodology 5
 1.3 Scope of the Report 6
 1.4 Executive Summary 7

 2. Technologies and Product Offering for High-Content Analysis 10
 2.1 Definition of High-Content Analysis and Why it is so Attractive a Discipline 11
 2.2 Classes of Measurements Possible with High-Content Analysis Approaches and Biologies Interrogated 14
 2.3 Instrumentation Platforms for High-Content Analysis 17
 2.3.1 High-Content Screening Technology 17
 2.4 Reagent and Assay Platforms for High-Content Analysis 24
 2.5 Cell-based Screening Technologies in Drug Development 28
 2.5.1 Applications of Cell-based Assays 28
 2.5.2 Pharma Drug Discovery Paradigm and Compound Screening 28
 2.5.3 High-Content Analysis in the Biopharmaceutical Industry 29

 3. Market Analysis of the High-Content Tools Space 31
 3.1 High-Content Analysis Market Size and Growth 31
 3.2 Market Survey to Assess Qualitative and Quantitative Parameters of the High-Content Analysis Space 31
 3.3 Experimental and Research Trends in High-Content Analysis 33
 3.4 Challenges and Market Drivers in High-Content Analysis 38
 3.4.1 Barriers to High-Content Analysis 40
 3.4.2 Drivers of High-Content Analysis 41
 3.5 High-Content Analysis in Combination with RNAi 41
 3.6 Market Landscape of Instrumentation for High-Content Analysis 43
 3.7 Reagents and Assays Usage in High-Content Analysis 47
 3.8 Trends in High-Content Analysis Assays/Reagents Space-Major Product Vendors 50
 3.9 Emerging Market Trends in High-Content Analysis 52
 3.10 Market Forecasts for the High-Content Analysis Space 54
 3.11 Use of HCS in Pharmaceutical Companies 56
 3.12 Qualitative Opportunities and Challenges for Market Adoption 57

 4. Strategic Analysis of the High-Content Tools Space 58
 4.1 High-Content Analysis Market Structure 58
 4.2 Description of the Drug Discovery Marketplace and Definition of the Field 58
 4.3 Key Market Drivers and Challenges in the High-Content Analysis Space 59
 4.4 Consolidated Picture of the High-Content Analysis Marketplace 62
 4.5 High-Content Analysis Market Sectors and Growth Rate 64
 4.6 Vendors of High-Content Analysis Technology 64

 5. High-Content Analysis Technology Platforms 65
 5.1 Methods of Digital Imaging 65
 5.2 Fluorescence Microscopy 65
 5.3 Major High-Content Analysis Instrumentation 66
 5.3.1 High-Content Analysis Platforms to Support GPCR Screening 67
 5.4 High-Content Analysis Reagents 67
 5.5 Imaging Software 68
 5.6 Enterprise-Level IT Solution to Support High-Content Screening Experiments 68
 5.6.1 Image Analysis Algorithms 69
 5.7 Use of RNAi in High-Content Analysis 70
 5.8 Industry Alliance to Leverage RNAi and High-Content Analysis 70
 5.9 Emerging Trends in High-Content Analysis Technology Platforms 71

 6. High-Content Analysis in Drug Selection, Screening and Biomarker Discovery 72
 6.1 Stem Cells Used as a Drug Discovery Tool 73
 6.2 Cellular Systems Biology for Development of Toxicity Panels in Drug Safety Testing 73
 6.3 Drug Discovery Companies Marketing Cell-based Assays 74
 6.4 Companies Using Cell-based Assays in Drug Discovery Programs 77
 6.4.1 Phenotypic Drug Discovery (PDD) 77
 6.4.2 Application of Quantitative High-Throughput Screening to High-Content Analysis of Cell-based Assays 78

For more information please contact :

http://www.aarkstore.com/reports/Cell-Based-Assays-for-Drug-Discovery-6634.html

http://blogs.aarkstore.com/

From:Aarkstore Enterprise
Contact: Neel
Email: press@aarkstore.com
URL: www.aarkstore.com

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