I wrote about
Deplinrecently. Billed as a 'medical food,' it is an fancy new methylated version of folate that easily enters the brain. Being a good sport and an inquiring mind as well as a doctor, I thought I'd give it a try.
The downside of Deplin is that it does indeed interfere with sleep. On the plus side, however, I have noticed an increased ability to focus on loathsome tasks involving numbers. My theory is that I have been borderline low on norepinephrine, the lack of which makes me inattentive and anxious. This new source of methylated folate is, perhaps, hard at work promoting norepinephrine production in my aging brain.
I have not yet heard back from several patients whom I have started on Deplin. I hope that it will improve their response to antidepressants and decrease that lethargy that sometimes accompanies the use of SSRIs. This side effect may be due to a down-regulation of norepinephrine receptors in the brain.
ca-pub-1793295148737117
The downside of Deplin is that it does indeed interfere with sleep. On the plus side, however, I have noticed an increased ability to focus on loathsome tasks involving numbers. My theory is that I have been borderline low on norepinephrine, the lack of which makes me inattentive and anxious. This new source of methylated folate is, perhaps, hard at work promoting norepinephrine production in my aging brain.
I have not yet heard back from several patients whom I have started on Deplin. I hope that it will improve their response to antidepressants and decrease that lethargy that sometimes accompanies the use of SSRIs. This side effect may be due to a down-regulation of norepinephrine receptors in the brain.