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Vitamin E Tocotrienols May Enhance Bone Health

Posted Oct 11 2013 10:11pm

Tocootrienols are a form of Vitamin E, abundant in annatto – derived from the seeds of the achiote trees of tropical and subtropical regions around the world.  Malaysian researchers employed a rat model of postmenopause, to which a dose of tocotrienols (human equivalent of 420 mg) was administered on a daily basis.  The team observed that the compound raised key markers of bone formation – osteoblasts, osteocalcin, and osteoid biosynthesis.  As well, tocotrienols decreased the breakdown of bone proteins and the extent of bone surface erosion.  

Abdul-Majeed A., Mohamed N., Soelaiman IN.  “Effects of tocotrienol and lovastatin combination on osteoblast and osteoclast activity in estrogen-deficient osteoporosis.” Evidence-Based Complementary and Alternative Medicine; doi: 10.1155/2012/960742.

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