An underlying cause of fatigue can be suboptimal mitochondrial function, and Vitamin D deficiency is a well-recognized cause of fatigue and myopathy. Akash Sinha, from Newcastle University (United Kingdom), and colleagues used non-invasive magnetic resonance scans to measure the response to exercise in 12 patients with severe deficiency before and after treatment with vitamin D. The team found that exercise recovery rates significantly improved after the patients took a fixed dose of oral vitamin D for 10-12 weeks, with the average phosphocreatine recovery half time decreasing from 34.4 sec to 27.8 sec. All patients reported an improvement in symptoms of fatigue after having taken the supplements. In a parallel study, the group demonstrated that low Vitamin D levels were associated with reduced mitochondrial function. Explaining that: “[Vitamin D] therapy augments muscle mitochondrial maximal oxidative phosphorylation following exercise in symptomatic, vitamin D deficient individuals,” the study authors submit that: “This finding suggests that changes in mitochondrial oxidative phosphorylation in skeletal muscle could at least be partly responsible for the fatigue experienced by these patients. For the first time, we demonstrate a link between vitamin D and the mitochondria in human skeletal muscle.”
Akash Sinha, Kieren Hollingsworth, Steve Ball, Tim Cheetham. “Improving the Vitamin D status of Vitamin D deficient adults is associated with improved mitochondrial oxidative function in skeletal muscle.” Journal of Clinical Endocrinology and Metabolism, 6 April 2013.
The extent of a person’s energy expenditure is a key determinant in risk reductions for hypertension, hypercholesterolemia, diabetes, and coronary heart disease
Printer generates material that can perform some of the basic functions of the cells inside the human body.
Vitamin D is vital for efficient muscle performance and may help to boost energy levels.
Living near asphalt that is sealed with coal tar may raise a person’s risk of getting cancer, with the greatest potential effect in young children.
Daily consumption of flaxseed may decrease insulin resistance and help reduce the risk of developing type-2 diabetes, among pre-diabetic men and women.
Lower levels of testosterone are predictive of rheumatoid factor (RF)-negative rheumatoid arthritis (RA), among men.
Women who consume walnuts regularly may reduce their risks of type-2 diabetes by as much as 24%.
Decreased levels of the hormone melatonin may be linked to the development of type 2 diabetes.
Consuming two servings of fatty fish per week may add as much as two extra years of lifespan.
Pharmaceuticals commonly found in the environment are disrupting streams, with unknown impacts on aquatic life and water quality.
Older athletes who engage in endurance training have longer telomere length, and maximal oxygen consumption positively associates with telomere length.
Exercising on watercycling machines helps people who have joint problems such as arthritis, or are overweight, to participate in aerobic activity.
Mesenchymal stem cells prevent post-traumatic arthritis, in a lab animal model.
Johns Hopkins researchers successfully use nanoscale artificial fiber scaffolds to help coax stem cells into developing into cartilage.
Resveratrol improves strength and endurance, in lab models.
Complementary & Alternative Medical (CAM) therapies as an adjunct to conventional medical care improves outcome measures.
Older men and women who regularly practice Tai Chi demonstrate improved expansion and contraction of arteries, as well as improved knee muscle strength.
Not only does lifting weights improve muscle power and promotes cardiovascular health, but doing so enhances quality of life as well.
University of Central Florida (US) team successfully uses stem cells to grow neuromuscular junctions between human muscle cells and human spinal cord cells.
Drinking a leucine-enriched protein drink whilst taking part in endurance exercise may boost muscle synthesis by a third.
Tip #153 - Fit with Fiber
Soluble fiber is found in foods such as oat/oat bran, dried beans and peas, nuts, barley, flax seed, fruits such as oranges and apples, vegetables such as carrots, and psyllium husk. It binds with fatty acids and prolongs stomach emptying time so that sugar is released and absorbed more slowly. Researchers from Hospital Universitari de Sant Joan (Spain) randomly assigned 200 overweight or obese study subjects to receive a daily soluble fiber supplement (comprised of Plantago ovata husk and glucomannan) two or three times a day, or placebo, for 16 weeks. At the end of the study, weight loss was higher in both fiber groups (4.52 and 4.60 kg lost, respectively), compared to the placebo group (0.79 kg weight loss). Additionally, LDL (low-density, “bad”) cholesterol levels decreased by 0.38 and 0.24 mmol/l in the fiber-supplemented groups, and the ratio of total cholesterol to HDL (high-density, “good")-cholesterol, and HDL to LDL, were also improved.
The recommended intake of fiber is 25 grams per day. To meet this, eat at least 5 servings of fruits & vegetables as well as at least 6 servings of grain products per day (at least 3 of which are whole grains). Your waistline, as well as cardiovascular health, will both benefit.