Vitamin D deficiency found in 76 percent of hip fracture patients
Posted Dec 16 2010 12:00am
IOFBoneHealth.org - A recent study has revealed high rates of vitamin D deficiency among hip fracture patients in New Delhi, India, confirming the conclusions of similar international studies which point to vitamin D deficiency as a risk factor for hip fracture.
A group of 90 hip fracture patients was compared to a matched control group of similar age, sex and co-morbidity. Of the patients who had suffered hip fractures, 76.7 percent were shown to be vitamin D deficient as measured by serum 25-hydroxyvitamin D levels [25(OH)D levels] of less than 20 ng/ml. In addition, 68.9 percent had elevated PTH levels. In comparison, only 32.3 percent of the controls had vitamin D deficiency and 42.2 percent had elevated PTH levels (secondary hyperparathyroidism).
Vitamin D deficiency has been linked to the pathogenesis of osteoporosis and is increasingly thought to play a role in muscle strength, certain cancers, multiple sclerosis and diabetes. Vitamin D levels are very low in the Indian population in all age groups, and could be explained by skin pigmentation, traditional clothing and the avoidance of sunlight.
The study (OC13) was presented at the IOF Regionals – 1st Asia-Pacific Regional Osteoporosis Meeting held in Singapore from December 10-13, 2010. All abstracts from the meeting have been published in Osteoporosis International, Vol. 21, Suppl. 5, 2010.
The results of the New Delhi study confirm that serum 25-hydroxyvitamin-D levels may be a useful index for the assessment of risk of hip fracture in elderly people.
IOFBoneHealth.org - A recent study has revealed high rates of vitamin D deficiency among hip fracture patients in New Delhi, India, confirming the conclusions of similar international studies which point to vitamin D deficiency as a risk factor for hip fracture.
A group of 90 hip fracture patients was compared to a matched control group of similar age, sex and co-morbidity. Of the patients who had suffered hip fractures, 76.7 percent were shown to be vitamin D deficient as measured by serum 25-hydroxyvitamin D levels [25(OH)D levels] of less than 20 ng/ml. In addition, 68.9 percent had elevated PTH levels. In comparison, only 32.3 percent of the controls had vitamin D deficiency and 42.2 percent had elevated PTH levels (secondary hyperparathyroidism).
Vitamin D deficiency has been linked to the pathogenesis of osteoporosis and is increasingly thought to play a role in muscle strength, certain cancers, multiple sclerosis and diabetes. Vitamin D levels are very low in the Indian population in all age groups, and could be explained by skin pigmentation, traditional clothing and the avoidance of sunlight.
The study (OC13) was presented at the IOF Regionals – 1st Asia-Pacific Regional Osteoporosis Meeting held in Singapore from December 10-13, 2010. All abstracts from the meeting have been published in Osteoporosis International, Vol. 21, Suppl. 5, 2010.
The results of the New Delhi study confirm that serum 25-hydroxyvitamin-D levels may be a useful index for the assessment of risk of hip fracture in elderly people.