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Ultracet As Effective As Gabapentin for Diabetic Nerve Pain

Posted Nov 04 2009 10:06pm 2 Comments

Ultracet, a combination of tramadol and acetaminophen, has been shown to be as effective as gabapentin (Neurontin) for treating painful diabetic neuropathy. The findings from this study, which was funded by Janssen, marketers of the medication, were presented at the World Diabetes Congress in Montreal. Gabapentin is a common first line treatment for nerve pain in diabetics. In the study, 139 patients with painful diabetic neuropathy were divided into two groups and assigned to receive tramadol/acetaminophen or gabapentin. After 6 weeks, both groups had similar improvements in pain.

Diabetic neuropathy is a nerve disorder caused by metabolic factors associated with diabetes. The condition causes numbness, tingling and other abnormal sensations, generally starting in the toes and progressing up the legs. Painful diabetic neuropathy can cause shooting, stabbing or electrical pain as well as intense burning pain on the bottom of the feet. The pain generally occurs at rest or during sleep, but in more severe cases can be more consistent. About 5% of diabetics will develop painful diabetic neuropathy.

More on diabetic neuropathy.

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Comments (2)
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I suffer from Fibromyalgia. Although prescribed 8 tablets daily, I typically take 4 if I can get away with it. It's very effective for pain.
I'm not quite sure why he'd say that, maybe there's a combo thing going on there and I'd make mention of it to your doctor next time you see them. I take Lexapro but do not take the Ultram anymore as I reacted to it badly years ago. I do take my Lexapro at night as I always forget to take those sorts of meds so it just helps me when I schedule my daily's outside of pain meds at the same time.
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