Health knowledge made personal
Join this community!
› Share page:
Go
Search posts:

Trace Elements Associated with Pancreatic Cancer Risk

Posted Jan 12 2012 10:13pm
Posted on 2012-01-10 06:00:00 in Cancer | Environment | Minerals |

Higher levels of cadmium, arsenic, and lead in the body appear to be associated with an increased risk of pancreatic cancer, according to results from a Spanish study.  Nuria Malats, from the Spanish National Cancer Center (Spain), and colleagues analyzed toenail clippings obtained from 118 patients with exocrine pancreatic cancer who were enrolled in the PANKRAS 2 Study, conducted in 1992-1995. For their control group, the team obtained toenail clippings from 399 participants in the Spanish Bladder Cancer/EPICURO Study of 1998-2001.  The toenail clippings, which had been stored at room temperature until analysis, had their trace elements quantified using inductively coupled plasma mass spectrometry. Samples also underwent acid digestion and gravimetric recording for assay purposes. A separate analysis was performed to assess median concentrations of trace elements between cases and controls. After confounding variables were excluded, the researchers found that exocrine pancreatic cancer risk was significantly increased among subjects whose concentrations of cadmium, arsenic, and lead were in the highest quartile. The researchers also found that levels of nickel and selenium were inversely associated with exocrine pancreatic cancer risk.  The study authors conclude that: “Novel associations are reported of lead, nickel and selenium toenail concentrations with pancreas cancer risk. Furthermore, the results confirm previous associations with cadmium and arsenic.”

Andre F S Amaral, Miquel Porta, Debra T Silverman, Roger L Milne, Manolis Kogevinas, Nathaniel Rothman, et al.  “Pancreatic cancer risk and levels of trace elements.”  Gut, 19 December 2011.



  
View Current Anti-Aging Newsletter!
Daily supplementation of folic acid and vitamin B12 help to improve brain functioning among older people.
A new way to deliver therapeutic human cells to diseased areas paves the way towards effectively using cell therapy to treat a variety of disorders.
DHEA (dehydroepiandrosterone), a hormone secreted by the adrenal glands, helps to alleviate menopausal symptoms.
Women who are at risk for breast cancer may also be at greater risk for heart disease.
Baylor College of Medicine (US) team reports that in a mouse model, mice learn and remember better when activity of a molecule known as PKR is inhibited in the
Higher levels cadmium, lead, and arsenic in the body associate with an increased risk of pancreatic cancer, whereas elevated levels of selenium and nickel assoc
Acupuncture significantly reduces levels of neuropeptide Y, a marker of chronic stress, in a lab animal model.
Italian researchers reveal that a molecule known as CREB1 is triggered by a low-calorie diet and promotes a healthy brain, in a lab animal model.
Mindfulness techniques reduce psychological distress and fatigue in people experiencing inflammatory rheumatic joint diseases.
A number of research groups are developing DNA-based circuits designed to be embedded in the human body, to monitor health and treat diseases before...



 
Post a comment
Write a comment:

Related Searches