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Tiny Factories to Produce Medicine Within the Body

Posted Jul 26 2012 10:09pm
Posted on July 25, 2012, 6 a.m. in Nanotechnology Drug Delivery Technology

Scientists from the Massachusetts Institute of Technology (Massachusetts, USA) report an advance toward treating disease with minute capsules containing not drugs but the DNA and other biological machinery for making the drug. Daniel G. Anderson and colleagues have devised micro- and nano-sized capsules that contain the genetically coded instructions, plus the read-out gear and assembly line for protein synthesis that can be switched on with an external signal. The resulting nanoparticles produced active proteins on demand when the researchers shined a laser light on them,  being turned on when needed to produce medicines that cannot be taken orally or are toxic and would harm other parts of the body.

Avi Schroeder, Michael S. Goldberg, Christian Kastrup, Yingxia Wang, Shan Jiang, Daniel G. Anderson, et al.  “Remotely Activated Protein-Producing Nanoparticles.”  Nano Lett., 2012, 12 (6), pp 2685–2689.

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Anti-Aging Therapeutics 13   View the Table of Contents
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13. Prevent Prostate Problems
Prostate cancer is a major cause of death among men. It has claimed the lives of 56,000 European men (1998), along with 29,900 American men (2004). To-date, there have been no obvious preventive strategies, however in 2005 scientists from the Northern California Cancer Center (USA) proposed that Vitamin D may cut prostate cancer risk. The researchers found that in men with certain gene variants, high sun exposure reduced prostate cancer risk by as much as 65%. Previous research has shown that the prostate uses Vitamin D...
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