Telomeres are the end caps of chromosomes, protecting the DNA complexes from deterioration during cell division. Telomere shortening is considered a marker of cellular aging, and prematurely shortened telomeres have been linked to increased risk of cancers, heart disease, dementia and death. John Carlquist, from the University of Utah (Utah, USA), and colleagues tested DNA samples from over 3,500 heart attack and stroke patients. They drew upon an archive of peripheral blood DNA samples collected from nearly 30,000 heart patients, with as much as 20 years of follow-up clinical and survival data. Correlating the data with samples tested, the team was able to predict survival rates among patients with heart disease based on the telomere lengths. The lead investigator comments that: "I believe telomere length could be used in the future as a way to measure the effectiveness of heart care treatment."
John Carlquist, Stacey Knight, Richard M. Cawthon, Benjamin Horne, Jeffrey Rollo, John Huntinghouse, J. Muhlestein, Jeffrey Anderson. “Telomere Length Is Associated with Survival, Patients Preferred for Angiography." Journal of the American College of Cardiology, Volume 61, Issue 10, Supplement, 12 March 2013, Page E1509.
Dietary supplementation of Vitamin D may help to lessen muscle fatigue and improve efficiency, among people with low blood levels of the vitamin.
Worse sleep quality may correlate to increased amyloid deposits in the brain, a marker of Alzheimer's Disease.
Women who take aspirin are at a reduced risk of developing melanoma, the deadliest form of skin cancer.
The extract of the Rosemary spice may lower blood glucose and cholesterol levels, as well as assist in weight management, in a laboratory animal model.
Researchers are able to predict survival rates and life expectancy among patients with heart disease, based on the length of the end caps of their chromosomes.
Australian researchers reveal that by targeting a single anti-aging enzyme, there exists the potential to prevent age-related diseases and extend lifespans.
A diet rich in cocoa – containing abundant amounts of flavonol antioxidants, may help to regulate insulin levels, in diabetics.
Non-smokers who are exposed to secondhand tobacco smoke are more likely to develop early signs of heart disease.
Dietary supplementation of omega-3 fatty acids from fish oil may help to protect against skin cancer.
Excess dietary salt may drive the development of multiple sclerosis, psoriasis, and other autoimmune diseases.
Worldwide, people are dying at older ages and early childhood survival rates have risen dramatically.
People may lose 30 minutes of life expectancy for every two cigarettes, for being 11 pounds overweight, and for eating an extra portion of red meat daily.
Optimal heart health in middle age helps the odds of living up to 14 years longer, free of cardiovascular disease.
Individuals with telomeres in the shortest 10% may be 23% more likely to die in the three years following measurement of these DNA endcaps.
Two United Nations agencies have mapped the intersection of health and climate in an age of global warming.
What and when we eat can alter our body clocks – consequently impacting overall health, weight, and life expectancy.
Why women live, on average, longer than men may be explained by genetic variation across mitochondria – the energy powerhouses of cells.
Harvard Medical School (US) team urges that the elimination of physical inactivity could reduce global rates deaths by all causes by at least 5.3m annually.
Phobic anxiety associates with shorter telomeres – a marker of a cellular aging, in middle-aged and older women.
A study analyzing 75 years of statistical data suggests that death rates in the United States are dropping.
Tip #141 - Men – Get Moving
Previous studies have suggested that physical activity decreases the risk of certain cancers. University of California, Los Angeles (USA) researchers have found that men who work in jobs that require a continuous level of high physical effort are at reduced risks of developing prostate cancer. The team compared the physical activity of 392 workers who developed prostate cancer with 1,805 men similarly employed and of similar age. Amongst a group of aerospace workers, 64% of whom were involved in work that required sustained and high levels of physical activity, the odds for prostate cancer were 45% lower, as compared to their less active counterparts.
Don’t underestimate the health benefits of physical activity, be it leisure-time exercise, competitive sports, or at-work exertion. Check with your anti-aging physician to make sure the level of your physical activity is appropriate for your medical needs.