Montmorency tart cherries have been found to activate PPAR isoforms (peroxisome proliferator activating receptors) in many of the body’s tissues. Studies suggest that anthocyanins – the pigments that give the fruit its red color – may be responsible for PPAR activation. E. Mitchell Seymour, from the University of Michigan (Michigan, USA), and colleagues compared the effect of tart cherries and a prescription drug that helps to regulate fat and glucose but for which long-term use can increase stroke risk. Employing a model of stroke-prone rats which were put through various physical tests, such as walking on a tapered beam and climbing a ladder, the researchers found that compared to the drug, tart cherry intake significantly improved balance and coordination, and at the same time lowered blood pressure. The study authors submit that: “intake of a physiologically-relevant amount of anthocyanins from tart cherry significantly reduced stroke-related phenotypes, was safer than [prescription drug], and may be a good preclinical model to explore the stroke-protective effects of an anthocyanin-rich diet.”
E. M. Seymour, J. Wolforth, K. Bosak, M. Kondoleon, V. Mehta, P. Brickner, S. F. Bolling. “Effect of tart cherry versus PPAR agonist pioglitazone on stroke-related phenotypes and inflammation” [Abstract 359.7]. Presentation at Experimental Biology 2013, 23 April 2013.
Enabling city dwellers to reconnect with nature, parks and urban gardens help to relieve mental distress and improve life satisfaction.
Microscopic dust particles may not only put airways at risk, but may compromise the cardiovascular system, liver, brain, and kidneys.
A cherry-rich diet may decrease stroke risk, suggests an animal study.
Obesity raises the risk of future prostate cancer, among men with an initial benign biopsy of the prostate.
Triterpenoids extracted from apple peel may influence expression of IP-10, a gene that is linked to inflammatory disorders including irritable bowel disease.
The ethyl ester form of omega-3 fatty acids may improve arterial stiffness, among obese men and women.
American Heart Association issues statement in support of aerobic exercise, resistance or strength training and isometric hand grip exercises to lower high bloo
Pinpointing cancer-associated changes in metabolism of cells may be an effective early detection technique.
Consuming grapes may help protect against organ damage associated with the progression of metabolic syndrome, an animal model reveals.
Elevated hair cortisol levels over time may correlate to an increased risk of cardiovascular disease.
Routine dental cleanings and treating periodontal disease may reduce a person’s risks of ischemic stroke.
Stroke and subclinical markers of vascular disease may be predicative of those older patients with type 2 diabetes who may develop cognitive decline.
A Mediterranean-style diet may curtail the risks of heart attack, stroke, and cardiovascular-related death
People who snore tend to have thickening or abnormalities in the carotid artery, which may be a precursor to atherosclerosis.
Consumption of eggs does not associate with an increased risk of heart disease or stroke.
Regional (US) stroke registry data suggests that stroke may be shifting from a disease of the elderly to a mid-life health concern.
Lycopene, an antioxidant compound that gives tomatoes their bright color, reduces the risk of stroke by up to 55%.
Meta-analysis of 34 studies indicates a significant association of shift work with myocardial infarction and ischemic stroke.
Researchers submit that by raising the Vitamin C recommended dietary allowance (RDA), cases of heart disease, stroke, and cancer might be slashed.
People with a history of mental illness are more likely to also have a chronic health condition, such as heart disease or diabetes.
Tip #167 - Snooze, Don’t Lose
Too little sleep compromises many of the body’s biological processes, most notably the immune system, metabolic function, and cognitive performance (specifically, learning and memory). Researchers from Beth Israel Deaconess Medical Center (Massachusetts, USA) reported that sleep is important for the development of episodic memories, and particularly those of an emotional nature. The team studied 88 college students, and found that those subjects who slept a full evening remembered the emotional scene they were shown in far greater detail, as compared to those participants who stayed awake for 12 hours after viewing the scene.
Defying the adage that ‘you snooze, you lose,’ sleep is a vital process that helps to preserve memories. Don’t underestimate the restorative role of sleep: while the amount of sleep required is highly individualized, it is critical to get sleep of a sufficient duration that is followed by a spontaneous awakening and leaves you feeling refreshed and alert for the day.