Successful Stem Cell Treatment of Spinal Cord Injury in Dogs
Posted Feb 08 2010 10:09pm
Histostem Participates in Successful Stem Cell Treatment for Acute Spinal Cord Injury in Dogs
February 08, 2010: 12:00 PM ET
Stem Cell Therapy International, Inc. (OTCBB: SCII) announced that Histostem Ltd. of South Korea (“Histostem”) has participated in a study resulting in the successful treatment of spinal cord injury in dogs through the use of Multipotent Stem Cells (MSCs) derived from Human Umbilical Cord Blood (HUCB). The study, a collaborative effort between a team of doctors from the Departments of Veterinary Surgery and Veterinary Anatomy at Konkuk University, Seoul, Korea and Dr. Hoon Han, President and Founder of Histostem, presented a method for the percutaneous transplantation of stem cells and investigated the therapeutic efficacy of transplanting stem cells to improve the recovery of the central nervous system following such acute spinal cord injury.
While previous research on spinal cord injury has typically used rats, this study used dogs which have a spinal cord structure more similar to humans. Within the test group, those dogs that received cellular transplants exhibited gradual improvement in hind limb locomotion two to three weeks after the transplant and also demonstrated reduced cyst and injury size.
Dr. Han commented, “Our research demonstrated a new, less invasive method of transplanting human umbilical cord blood derived multipotent stem cells, which avoids surgical exposure and allows the cells to be more precisely transplanted into the spinal cord. In addition to this breakthrough in the technique used to transplant stem cells, we also had success in improving the condition of the spinal cord injury among the test group. Based on the successful results of this study and because of the canine spinal cord’s resemblance to a human spinal cord, we are optimistic that this technique has many potential applications in the treatment of human spinal cord injury through stem cell transplantation.”
More details on the research process and results are available in the December 2009 issue of the Journal of Neurosurgery: Spine.