Study Provides New Evidence On The Risk Of Heart Attack Associated With Use Of Popular Anti-Inflammatory Drugs
Posted Sep 28 2011 5:47pm
An international study led by the Hull York Medical School has found that the use of popular non-steroidal anti-inflammatory drugs can increase the risk of heart attack or stroke by a third.
Researchers from the Hull York Medical School (HYMS) and the Institute for Clinical Evaluative Sciences in Canada carried out a systematic review of controlled observational studies. They found that in patients with heart problems, or those with cardiovascular risk factors, use of non-steroidal anti-inflammatory drugs (NSAIDs) including diclofenac and indomethacin was significantly associated with an increase in the risk of serious cardiovascular events such as heart attack and stroke.
Other common NSAIDs, including naproxen and low doses of ibuprofen do not appear to be associated with an increase in risk.
The results of the study, which involved examining and combining data from 51 large scale studies conducted in Europe, USA, Canada and Australia, are published in PLoS Medicine this week.
An international study led by the Hull York Medical School has found that the use of popular non-steroidal anti-inflammatory drugs can increase the risk of heart attack or stroke by a third.
Researchers from the Hull York Medical School (HYMS) and the Institute for Clinical Evaluative Sciences in Canada carried out a systematic review of controlled observational studies. They found that in patients with heart problems, or those with cardiovascular risk factors, use of non-steroidal anti-inflammatory drugs (NSAIDs) including diclofenac and indomethacin was significantly associated with an increase in the risk of serious cardiovascular events such as heart attack and stroke.
Other common NSAIDs, including naproxen and low doses of ibuprofen do not appear to be associated with an increase in risk.
The results of the study, which involved examining and combining data from 51 large scale studies conducted in Europe, USA, Canada and Australia, are published in PLoS Medicine this week.