Study Examines HIV Treatment Response In Men And Women
Posted Sep 20 2010 6:18pm
A new landmark study, which demonstrated it is possible to recruit large numbers of women into a clinical trial evaluating treatments for HIV infection, found no significant gender-based differences in response to the anti-HIV drugs darunavir and ritonavir — at least among those who remained in the trial to the end.
However, women dropped out of the GRACE (Gender, Race and Clinical Experience) study at higher rates than men for reasons other than drug failure, indicating that more must be done to retain women in clinical trials that shed important light on the effectiveness of drugs in development or those on the market.
The study, published in the Sept. 21 issue of Annals of Internal Medicine, showed that nearly one-third of women dropped out, compared with less than one-fourth of the men enrolled.