Health knowledge made personal
Join this community!
› Share page:
Go
Search posts:

Stem Cells Engineered to Become Brain Cells

Posted Mar 28 2011 10:08pm
Posted on 2011-03-28 06:00:00 in Alzheimer's Disease | Stem Cell |

An early substantial loss of basal forebrain cholinergic (BFC) neurons  is a predominant feature of Alzheimer's disease and is associated leads to memory-retrieval problems, one of the most disabling aspects of the illness.   Christopher John Bissonnette, from Northwestern University's Feinberg School of Medicine (Illinois, USA), and colleagues coaxed embryonic stem cells to become BFC replacement cells, sufficiently stable to survive indefinitely under laboratory conditions.  Once implanted in to laboratory mice, the researchers found that the new neural material sent out connecting fibers to the hippocampus and appeared to function in the same way as the naturally occurring BFC cells.  The researchers conclude that: “The ability to selectively control the differentiation of human embryonic stem cells into [basal forebrain cholinergic (BFC) neurons] is a significant step …  for the development of both cell-transplant-mediated therapeutic interventions for Alzheimer's disease.”

Christopher John Bissonnette, Ljuba Lyass, Bula J Bhattacharyya, Abdelhak Belmadani, Richard J Miller, John A Kessler.  “The Controlled Generation of Functional Basal Forebrain Cholinergic Neurons from Human Embryonic Stem Cells.”  Stem Cells, March 4, 2011.


Northwestern University (US) scientists turn human embryonic stem cells in to a type of brain cell that is lost in Alzheimer's disease.
Regrowth of key adult brain cells (neurogenesis) is linked to the benefits of exercise as a stress reducer.
Review of 160 published studies confirms a compelling connection between a positive state of mind and overall health and longevity.
Caspases, a family of enzymes, play a role in the inflammatory process associated with Alzheimer’s and Parkinson’s Diseases.
Bursts of brain waves known as "sleep spindles" promote networking between key regions of the brain involved with learning.
US CDC reports that in 2009, life expectancy in the US rose to 78.2 years, and that the US age-adjusted death rate was 2.3% lower in the same year.
Swedish researchers confirm that polyphenol compounds in cocoa help to reduce elevated blood pressure.
Analysis of 97 studies involving 820,900 subjects finds that diabetes and fasting blood sugars >100 mg/dL associate with increased all-cause mortality.
Analysis of 50 published studies confirms the effects of the Mediterranean diet on waist circumference, HDL cholesterol, blood pressure, and glucose metabolism.
Women who are obese and not physically active may be at increased risk of triple-negative breast cancer.

  
View Current Anti-Aging Newsletter!
Second Opinion with Dr. Ron Klatz Solutions to improve your life, and your lifespan too.
radio tower Dr. Ronald Klatz, A4M physician founder, interviews the world’s top anti-aging experts in health, longevity, brain fitness, aesthetic beauty, and more. Get the answers to look and feel twenty years younger today.
Tune in to Second Opinion with Dr. Ronald Klatz. »
U.S. Events
congresses
Orlando Anti-Aging Conference Event
symposiums
workshops
  • Bio-Identical Hormone Replacement Therapy (BHRT) Symposium
  • Integrative Approaches to Practice Development
workshops
Workshops
  • Practice Management Workshop
fellowships
fellowships
International Events

 
Post a comment
Write a comment: