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Statins Associated with Lower Cancer Recurrence Following Prostatectomy

Posted Jun 28 2010 6:36pm

Men who use statins to lower their cholesterol are 30 percent less likely to see their prostate cancer come back after surgery compared to men who do not use the drugs, according to researchers at Duke University Medical Center. Researchers also found that higher doses of the drugs were associated with lower risk of recurrence.

The findings are published in the journal CANCER.

“The findings add another layer of evidence suggesting that statins may have an important role in slowing the growth and progression of prostate cancer,” says Stephen Freedland, MD, a member of the Duke Prostate Center and the Urology Section at the Durham Veterans Affairs Medical Center, and the senior author of the study. “Previous studies have shown that statins have anti-cancer properties, but it’s not entirely clear when it’s best to use them — or even how they work.”

Researchers examined the records of 1319 men who underwent radical prostatectomy included in the Shared Equal Access Regional Cancer Hospital (SEARCH) database. They found that 18 percent of the men -– 236 -– were taking statins at the time of surgery.

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