Health knowledge made personal
Join this community!
› Share page:
Go
Search posts:

Short Telomeres Linked to Risk for Common Cold

Posted Mar 13 2013 10:25pm
Posted on March 12, 2013, 6 a.m. in Infectious Disease

Telomeres are the end caps of chromosomes, protecting the DNA complexes from deterioration during cell division. Telomere shortening is considered a marker of cellular aging, and prematurely shortened telomeres have been linked to increased risk of cancers, heart disease, dementia and death.  Sheldon Cohen, from Carnegie Mellon University (Pennsylvania, USA), and colleagues enrolled 152 men and women, ages 18 to 55 years, measuring each subject’s telomere length on four types of immune cells: peripheral blood mononuclear cells, CD4-positive cells, CD8 cells positive for CD28, and CD8 cells negative for CD28.  Participants spent 24 hours in the laboratory under quarantine and then were given nasal drops containing 100 tissue culture infectious doses of rhinovirus 39. They were monitored for 5 days for development of cold symptoms. Relative risks for becoming infected by either of these definitions ranged from 1.22 for each standard deviation decrease in telomere length on peripheral blood mononuclear cells, to 1.38 on CD8/CD28-negative cells.  For clinical illness, each standard deviation decrease in telomere length brought a significant increase in risk only for measurements on CD8/CD28-negative cells.  Further, the team observed that for telomere length measured in all four cell types, about 80% of individuals in the shortest tertile became infected, compared with fewer than 60% in the longest tertile.  Only when telomere length was measured in CD8/CD28-negative cells was there a significant difference in clinical illness rates among tertiles: about 25% of those in the shortest tertile developed clinical colds versus about 13% of the longest tertile.  The study authors conclude that: “shorter CD8CD28− T-cell telomere length was associated with increased risk for experimentally induced acute upper respiratory infection and clinical illness.”

Sheldon Cohen, Denise Janicki-Deverts, Ronald B. Turner, Margaretha L. Casselbrant, Ha-Sheng Li-Korotky, Elissa S. Epel, William J. Doyle.  “Association Between Telomere Length and Experimentally Induced Upper Respiratory Viral Infection in Healthy Adults.”  JAMA. 2013;309(7):699-705.

  
A large study of 500,000 older adults followed for about 12 years reveals that as coffee drinking increases, the risk of death decreases.
Adolescents and young adults with a range of cardiometabolic risk factors have an increased risk of dying before they turn 55.
From Australia to Great Britain, researcher teams confirm that the more a person sits, the greater the risk of chronic diseases.
Individuals with shortened telomeres are at an increased risk of contracting colds, in a laboratory setting.
A Mediterranean-style diet may curtail the risks of heart attack, stroke, and cardiovascular-related death
Elevated levels of ozone and fine particulate matter in ambient air correlate to increased incidence of out-of-hospital cardiac arrests.
Canadian team reports that taking music lessons before the age of 7 years helps to create stronger connections in the brain.
Higher levels of thrombogenic microvesicles may raise the risk of developing white matter hyperintensities (WMH) in the brain, among postmenopausal women, blood
Marital quality may play key, yet under identified, role in patients’ health.
Two common perfluorinated chemicals (PFCs) – present in products such as fabrics and personal care products – may raise the risk of osteoarthritis.
Two United Nations agencies have mapped the intersection of health and climate in an age of global warming.
Extract of mung bean (Vigna Radiata) is shown to counteract the life-threatening condition known as sepsis, persistent and constant inflammation that can cause
Study results suggest that daily vitamin D supplementation can reduce the risk of aqcuiring respiratory infections in winter.
Severe influenza and exposure to high-intensity vibrations raise a person’s risks of developing Parkinson's Disease later in life.
People who drink hot tea or coffee are 50% less likely to carry methicillin-resistant Staphylococcus aureus (MRSA) in their noses.
The World Health Organization (WHO) warns that medical errors and hospital-acquired infections injure more people each year than airplane travel.
Exophiala species black yeast fungi show remarkable tolerance to heat, high salt concentrations, aggressive detergents, and to both acid and alkaline water.
Cellphones used by hospital patients and their visitors are twice as likely to contain potentially dangerous bacteria, compared to those of healthcare workers.
A study on mice shows that granulocyte macrophage-colony stimulating factor significantly reduces symptoms and prevents death after a lethal dose of flu virus.
Dietary fiber may reduce the risks of death from cardiovascular, infectious and respiratory diseases, or death from any cause over a 9-year period.
Anti-Aging Forum MLDP Join A4M
Tip #134 - “C” the Way to Lower Stroke Risk
A ten-year long European study involving 20,649 men and women found that increased blood levels of Vitamin C reduce the risk of stroke by 42%. University of Cambridge (United Kingdom) researchers revealed that both consumption of Vitamin C-rich foods and dietary vitamin supplements were equivalent in providing stroke-reducing benefits. They found that an optimal blood level of Vitamin C was reached after study subjects ingested five servings of fruits and vegetables.

A potent antioxidant that protects against free radical cellular damage, Vitamin C is found in abundantly in citrus fruit and juices, strawberries, blueberries, rose hips, cantaloupes, tomatoes, and red bell peppers.

Because Vitamin C is easily destroyed by cooking, opt to eat your fruits and vegetables raw. As well, because Vitamin C levels drop as foods are stored, buy as is locally available and consume immediately after purchase.
 
Post a comment
Write a comment:

Related Searches