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Severe Morning Sickness Patients Get Relief from Anti-Seizure Drug

Posted Dec 07 2012 6:28pm

Good news may be on the horizon for Kate Middleton, Duchess of Cambridge, and other women stricken with severe nausea and vomiting during pregnancy, thanks to the work of a University at Buffalo professor who is conducting research on a drug that is showing success treating pregnant women with this condition.

Thomas Guttuso Jr., MD, assistant professor of neurology in the UB School of Medicine and Biomedical Sciences, has been studying the drug gabapentin, an anti-seizure and anti-pain drug that he previously had studied in cancer patients receiving chemotherapy.

“I became interested in this drug for hyperemesis gravidarum (an extreme form of morning sickness) because I saw how effective it appeared to be in treating chemotherapy-induced nausea and vomiting in patients who had failed treatment with conventional anti-emetics,” says Guttuso. Anti-emetics are drugs currently approved for treating nausea and vomiting.


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