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Role of Obesity in Future Prostate Cancer Risk

Posted May 24 2013 10:08pm
Posted on May 23, 2013, 6 a.m. in Men's Health Cancer Weight and Obesity

In that previous studies suggest that obesity associates with risk of high-grade prostate cancer, Andrew Rundle, from Columbia University (New York, USA), and colleagues assessed the role of obesity in the risk of future prostate cancer, among men with an initial benign biopsy of the prostate.  The team followed 6,692 men who were biopsied or underwent or transurethral resection of the prostate (TURP) with benign findings, conducting a nested case-control study of 494 prostate cancer cases and controls.  After taking into account factors including family history of prostate cancer, the researchers concluded that obesity at the time of the initial biopsy was associated with a 57% increased risk of developing prostate cancer during the 14 years of follow-up.  The study authors conclude that: “Obesity is associated with the presence of [prostatic intraepithelial neoplasia] in benign specimens and with future prostate cancer risk after an initial benign finding.”

Andrew Rundle, Michelle Jankowski,  Oleksandr N. Kryvenko, Deliang Tang, Benjamin A. Rybicki.  “Obesity and Future Prostate Cancer Risk among Men after an Initial Benign Biopsy of the Prostate.”  Cancer Epidemiol Biomarkers. April 23, 2013.

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Tip #167 - Snooze, Don’t Lose
Too little sleep compromises many of the body’s biological processes, most notably the immune system, metabolic function, and cognitive performance (specifically, learning and memory). Researchers from Beth Israel Deaconess Medical Center (Massachusetts, USA) reported that sleep is important for the development of episodic memories, and particularly those of an emotional nature. The team studied 88 college students, and found that those subjects who slept a full evening remembered the emotional scene they were shown in far greater detail, as compared to those participants who stayed awake for 12 hours after viewing the scene.

Defying the adage that ‘you snooze, you lose,’ sleep is a vital process that helps to preserve memories. Don’t underestimate the restorative role of sleep: while the amount of sleep required is highly individualized, it is critical to get sleep of a sufficient duration that is followed by a spontaneous awakening and leaves you feeling refreshed and alert for the day.

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