REFLUX SYMPTOM REPORTING AND ACID PERFUSION TESTING IN SCLERODERMA.
Posted Nov 19 2009 10:03pm
By Gibbons, M.J.; Watson, R.G.P.; Johnston, B.T
Gastroesophageal reflux disease causes significant morbidity in scleroderma (SSc) yet the reliability of reflux symptoms in the diagnosis is unclear. Acid perfusion testing (APT) has produced conflicting results regarding acid insensitivity in SSc patients. The aim of this study was to assess the value of reflux symptom reporting in predicting acid reflux in SSc and to assess the diagnostic value of acid perfusion testing in SSc-associated acid reflux.
Patients complaining of heartburn and/or acid regurgitation and who fulfilled the ACR diagnostic criteria for SSc were recruited. Acid suppression was discontinued for at least 3 days prior to assessment. Reflux symptoms were quantified using a scoring system for each of heartburn and acid regurgitation with total minimum and maximum scores of 0 and 6 (0=[less than]x1/month, 3=daily symptoms). (Read More....)