Protein That Fuels Lethal Breast Cancer Growth Emerges as Potential New Drug Target
Posted Oct 18 2011 7:39am
A protein in the nucleus of breast cancer cells that plays a role in fueling the growth of aggressive tumors may be a good target for new drugs, reports a research team at the Duke Cancer Institute.
The finding, published in the October 18, 2011, print issue of the journal Cancer Cell, presents a potential new way to inhibit breast cancer growth among so-called estrogen receptor negative cancers, which are especially lethal because they don’t respond to current hormone therapies.
“This is validation of a new drug target for a subset of breast cancers that have poor treatment options,” said the study’s senior author, Donald McDonnell, PhD, chairman of the Duke Department of Pharmacology and Cancer Biology.