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Plastics Compound May Precipitate Prostate Cancer

Posted Jul 11 2013 10:08pm

Bisphenol A (BPA) is a synthetic compound commonly found in plastics and the linings of food cans.  The chemical has been the focus of recent concerns as data suggests that BPA acts as an endocrine disruptor in the human body, alters the body's hormonal balance by replicating the activity of naturally occurring estrogen.  Gail S. Prins, from the University of Illinois/Chicago (Illinois, USA), and colleagues used human prostate stem cells from organ donors to grow prostate tissue in a mouse model. They found that early BPA exposure significantly increased the risk of both prostate cancer and a precancerous condition known as prostate epithelial neoplasia (PIN). The incidence rates for PIN and prostate cancer were  12% of non-BPA exposed tissue, and 33-45% of tissue exposed to BPA.  The lead study author warns that: “These results suggest that stem cells are direct BPA targets which may explain the long-lasting effects of this chemical throughout the body.  They provide the first direct in vivo evidence that developmental exposure to environmentally relevant levels of BPA increases human prostate cancer risk."

Prins GS, et al.  Presented at ENDO 2013 (Annual Meeting of The Endocrine Society), June 17, 2013.

  
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Tip #187 - Milk The Benefits
Dairy and dairy products have been studied extensively for their promising health benefits:

• Combat Heart Disease & Stroke: University of Reading (United Kingdom) researchers studied findings from 324 studies of milk consumption as predictors of coronary heart disease (CHD), stroke and, diabetes. Data on milk consumption and cancer were based on the recent World Cancer Research Fund report. The team found that drinking milk can lessen the chances of dying from illnesses such as coronary heart disease and stroke by up to 15-20%. Separately, researchers from Bristol University (United Kingdom) studied data from the Carnegie (“Boyd Orr”) survey of diet and health in pre-war Britain. Tracking the lives and the dairy intake of 4,374 children between 1948 and 2005, the researchers found that 1,468 (34%) of them had died, and 378 of those deaths were caused by coronary heart disease and 121 were due to stroke. Not only did the study suggest that dairy rich diets in childhood do not contribute to heart problems later, the team found that higher childhood calcium intake was associated with lower stroke mortality. In addition, children who were in the group that had the highest calcium intake and dairy product consumption were found to have lower mortality rates than those in the lower intake groups.

• Maintain Cognitive Health: Researchers from the University of Oxford (United Kingdom) studied whether foods rich in Vitamin B-12 might counter homocysteine, a compound for which high levels are linked to an increased risk of heart disease and cognitive decline including Alzheimer's Disease. The team monitored 5,937 subjects in two age groups (47-49 years, and 71-74 years) participating in the Hordaland Homocysteine Study in Norway, surveying them for their daily food intake patterns. The team observed that those subjects with low B-12 levels suffered twice as much brain shrinkage as compared to those study participants with higher blood levels of the vitamin. The researchers observed two glasses of skim milk daily can help that raise plasma vitamin B-12 levels.
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