A study of more than 6,000 people has revealed that those with "metabolic abnormalities" may experience a faster decline in their cognitive skills. Archana Singh-Manoux, PhD, of INSERM, the French research institute in Paris and University College London in England, and colleagues gathered information on body mass index (BMI) and metabolic risk factors from 6,410 people with an average age of 50. Participants were defined as having metabolic abnormality if they had two or more of the following risk factors: high blood pressure or taking medication for it; low HDL-cholesterol; high blood sugar or taking diabetes medication; high triglycerides; or taking medication to lower cholesterol. Participants also took tests on memory and other cognitive skills at the start of the study and three times over the course of the next 10 years. Results showed that participants who were both obese and metabolically abnormal experienced a 22.5% faster decline in their cognitive test scores than those who were of normal weight without metabolic abnormalities. Metabolically normal obese individuals also experienced a more rapid decline than their non-obese and metabolically normal peers. Dr Singh-Manoux concluded:"More research is needed to look at the effects of genetic factors and also to take into account how long people have been obese and how long they have had these metabolic risk factors and also to look at cognitive test scores spanning adulthood to give us a better understanding of the link between obesity and cognitive function, such as thinking, reasoning and memory.
Singh-Manoux A, Czernichow S, Elbaz A, Dugravot A, Sabia S, Hagger-Johnson G, Kaffashian S, Zins M, Brunner EJ, Nabi H, Kivimäki M. Obesity phenotypes in midlife and cognition in early old age: The Whitehall II cohort study. Neurology. 2012;79:755-762.
Metabolic abnormalities such as obesity and high blood pressure may accelerate cognitive decline, say researchers.
Anthocyanins, antioxidant pigments found in fruit and vegetables, have been found to improve the blood lipid profile of people with high cholesterol.
New research suggests that exercising for just 30 minutes is as effective for weight loss as a whole hour.
Spouses of people who have a sudden heart attack are at increased risk of depression, anxiety, and suicide, even if their partner survives.
Regular consumption of olive oil may help to reduce cardiovascular risk by improving the function of cells that line the blood vessels.
Exposure to a compound produced when food is cooked with dry heat has been linked to the development of abdoinal obesity, and type 2 diabetes in mice.
Drinking three cups of green tea each day shown to help elderly people with metabolic syndrome lose weight and trim their waistline.
A commercially available acai berry product has been found to significantly lengthen the lifespan of fruit flies.
Study results suggest that daily vitamin D supplementation can reduce the risk of aqcuiring respiratory infections in winter.
People with severe coronary artery disease have been found to have higher-than-normal levels of the plastic bisphenol-A (BPA) in their urine.
Difficulty falling or staying asleep, or sleeping too much, may associate with cardiovascular and metabolic problems.
The body’s absorption of high fructose corn syrup (HFCS) and table sugar (sucrose) differs, with potential ramifications for metabolic dysfunction, blood pressu
Drinking a barley extract-enriched beverage may help to improve insulin sensitivity and prevent against type 2 diabetes.
Betulin, a compound found in abundance in birch bark, blocks a key pathway involved in cholesterol production.
Healthy people who are genetically predisposed to develop type 2 diabetes are also predisposed to weight gain.
One’s risk of future chronic disease may be impacted by factors beyond body mass index (BMI).
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46. Hormone Health: DHEA
Dehydroepiandrosterone (DHEA) is the most abundant hormone in the human body. It is involved in the manufacture of testosterone, estrogen, progesterone, and corticosterone. The decline of DHEA with age parallels that of HGH (see Tip 43), so by the age of 65, our bodies make only 10 to 20% of what they did at age 20.
DHEA supplementation has been shown in various clinical studies to enhance the immune response against infection. It also has been reported to be valuable against cancer, coronary artery disease, and osteoporosis. DHEA also increases muscle mass and reduces fat mass...