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Novel Technique Produces Stem Cells from Peripheral Blood

Posted Dec 09 2012 10:09pm
Posted on Dec. 6, 2012, 6 a.m. in Stem Cell Regenerative Medicine

Stem cells are unique in that they possessed the characteristic to self renew and can differentiate into multiple cell types (pluripotency).  A number of studies suggest their potential therapeutic value in regenerative medicine.  Gustavo Mostoslavsky, from Boston University (Massachusetts, USA), and colleagues utilize a lentiviral vector to efficiently produce high quality, induced pluripotent stem cell lines. Explaining that: "the ease of obtaining the tissue sample combined with the high efficiency of reprogramming makes this method a very valuable tool in the field,” the study authors submit that: "This protocol is simple, robust and highly consistent, providing a reliable methodology for the generation of human iPSCs from readily accessible 4 ml of blood.”

Sommer AG, Rozelle SS, Sullivan S, Mills JA, Park SM, Smith BW, Mostoslavsky G, et al.  “Generation of Human Induced Pluripotent Stem Cells from Peripheral Blood Using the STEMCCA Lentiviral Vector.”  J Vis Exp. 2012 Oct 31;(68). pii: 4327.

  
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