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Nonpathogenic Bacteria, Paenibacillus alvei, Useful as a Natural Biocontrol Agent for Elimination of Food-borne Pathogenic Bacte

Posted Apr 23 2012 12:00am

Description of Invention:
This newly isolated non-pathogenic bacterial strain (TS-15) has shown the ability to kill or inhibit a wide variety of harmful bacteria including many of the most common food-borne pathogens such as Salmonella, Escherichia, Listeria, Shigella, Enterobacter and Staphylococcus. The TS-15 stain may provide a natural low cost means to help protect the food supply. The strain may be used as a biocontrol agent in the form of a pesticide or pretreatment to soils in which fruits and vegetable are grown. Preventative use of the TS-15 strain in biocontrol measures may prevent many of the millions of illnesses in the U.S. that are caused by food-borne pathogens each year. Such prevention may also reduce the associated costs of treatment for such illnesses. Furthermore, isolation and development of the antibiotic compounds produced by the TS-15 strain may yield useful new compositions to help treat bacterial illness, including infections by some pathogens resistant to standard antibiotics.

  • Agriculture - pesticide
  • Medicine - antibiotic

Low cost natural means of prevention of many food-borne bacterial illnesses

Development Status:

Eric W Brown (FDA)
Jie Zhang (FDA)

Collaborative Research Opportunity:
The FDA Center for Food Safety and Applied Nutrition is seeking statements of capability or interest from parties interested in collaborative research to further develop, evaluate or commercialize Paenibacillus alvei (TS-15). For collaboration opportunities, please contact Alice Welch at .

For Licensing Information Please Contact:
Edward (Tedd) Fenn
NIH Office of Technology Transfer
6011 Executive Blvd. Suite 325,
Rockville, MD 20852
United States
Phone: 301-435-5031
Fax: 301-402-0220

Ref No: 2396

Updated: 04/2012

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