An estimated one-third of Americans take a daily multivitamin supplement, the composition of which mimics healthy fruit and vegetable compounds. J. Michael Gaziano, from Harvard Medical School (Massachusetts, USA), and colleagues analyzed data collected in the Physicians' Health Study (PHS) II, that includes 14,641 male U.S. physicians, initially age 50 years or older. Subjects received a daily multivitamin or equivalent placebo, and were followed for an average of 11.2 years. During multivitamin treatment, there were 2,669 confirmed cases of cancer, including 1,373 cases of prostate cancer and 210 cases of colorectal cancer, with some men experiencing multiple events. A total of 2,757 (18.8%) men died during follow-up, including 859 (5.9%) due to cancer. Analysis of the data indicated that men taking a multivitamin had a modest 8% reduction in total cancer incidence. The researchers found that a multivitamin significantly reduced the risk of total cancer (excluding prostate cancer - the early stage of which was the cause of half of all incident cancers in the study). There were no statistically significant reductions in individual site-specific cancers, including colorectal, lung, and bladder cancer, or in cancer mortality. Reporting that: “Daily multivitamin use was associated with a reduction in total cancer among 1312 men with a baseline history of cancer,” the study authors conclude that: “In this large prevention trial of male physicians, daily multivitamin supplementation modestly but significantly reduced the risk of total cancer.”
Gaziano J, Sesso HD, Christen WG, et al. Multivitamins in the Prevention of Cancer in Men: The Physicians' Health Study II Randomized Controlled Trial. JAMA. 2012;():1-10. Oct. 17, 2012; doi:10.1001/jama.2012.14641.
Increased dietary consumption of fish may lower stroke risk by up to 13%.
International Agency for Research on Cancer reports that cancer caused 7.6 million deaths in 2008, but its greater burden is in disability-adjusted life-years
Laboratory model supports theory that fat tissue creates an environment that is promotes tumor growth.
Eating a diet laden with carbohydrates raises the risk of developing mild cognitive impairment by four times; sugars raise that risk 1.5 times.
A strong social network, good self esteem, and a purpose in life correlate with increased bone mineral density.
Increased blood levels of Vitamin B-6 and Coenzyme Q10 associate with a reduced risk of coronary artery disease.
Analysis of data collected on 14,641 male physicians reveals the cancer preventive effect of long-term daily multivitamin supplementation.
University students who chew gum self-report reduced stress levels and greater productivity.
Soccer (football outside the US) helps men with high blood pressure to improve their fitness, normalize their blood pressure. and reduce their risk of stroke.
Found in green leafy vegetables, increased consumption of phylloquinone (Vitamin K1) may lower the risk of developing type-2 diabetes by as much as 51%.
Curcumin, the spice compound that gives curry its yellow color and pungent flavor, may inhibit formation of metastases, in a lab model of prostate cancer.
Eating red meat that has been cooked at high temperatures has been shown to significantly increase the risk of developing prostate cancer.
More than 6% of Americans ages 70 to 89 develop mild cognitive impairment (MCI) every year, and the condition appears to affect men more than women.
Study results suggest that men who take a daily vitamin E supplement may increase their risk of prostate cancer.
Married men with two or more children may be at significantly lower risk for having a fatal cardiovascular event
Being born and raised in a major urban area is associated with greater lifetime risk for anxiety and mood disorders.
Levels of nine specific proteins that decline with age can be reversed by testosterone treatment, suggesting beneficial effects for aging men.
Harvard researchers report that increased intakes of vitamin D associate with a reduced risk of cardiovascular disease in men.
Sulforaphane, one of the primary phytochemicals in broccoli, selectively targets and kills cancer cells while leaving normal prostate cells healthy.
Men who take 30 tablets a month or more of acetaminophen for five or more years have an estimated 38% lower risk of prostate cancer.
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#72 - Sin of the Skin #3: Thin Skin
As we age, the skin becomes papery thin, and suffers from a decrease in oil gland activity (which also may cause skin to become dry). Largely a function of hormonal decline, you may benefit from a hormone replacement regimen. Consult an anti-aging physician, who will follow these guiding principles to design your hormone replacement therapy (HRT) regimen:
• Use natural, not synthetic, agents
• Select bioidentical hormones, which the body is able to use safely and efficiently
• Prescribe proper dosing (as stipulated by laboratory testing for deficits), not supraphysiologic dosing
• Conduct regular follow-up office visits and lab tests, to monitor progress